apolipoprotein E : KMLE 의학 검색 엔진 - 의학사전, 의학용어, 의학약어, 의학논문, 약품/의약품 검색

MeSH(Medical Subject Headings) 맞춤 검색 (http://www.nlm.nih.gov) 결과 : 3 페이지: 1

Apolipoprotein E2 - 새창 One of three major isoforms of apolipoprotein E. In humans, Apo E2 differs from APOLIPOPROTEIN E3 at one residue 158 where arginine is replaced by cysteine (R158--C). In contrast to Apo E3, Apo E2 displays extremely low binding affinity for LDL receptors (RECEPTORS, LDL) which mediate the internalization and catabolism of lipoprotein particles in liver cells. ApoE2 allelic homozygosity is associated with HYPERLIPOPROTEINEMIA TYPE III.
Synonyms : APOE-epsilon 2, APOE-epsilon2, Apo E-2, Apo E2, ApoE2, Apolipoprotein E-2, Apolipoprotein E-epsilon2, APOE epsilon 2, APOE epsilon2, Apo E 2, Apolipoprotein E 2, Apolipoprotein E epsilon2
Apolipoprotein E3 - 새창 A 34-kDa glycosylated protein. A major and most common isoform of apolipoprotein E. Therefore, it is also known as apolipoprotein E (ApoE). In human, Apo E3 is a 299-amino acid protein with a cysteine at the 112 and an arginine at the 158 position. It is involved with the transport of TRIGLYCERIDES; PHOSPHOLIPIDS; CHOLESTEROL; and CHOLESTERYL ESTERS in and out of the cells.
Synonyms : APOE-epsilon 3, APOE-epsilon3, Apo E-3, Apo E3, ApoE3, Apolipoprotein E-3, Apolipoprotein E-epsilon3, Isoapolipoprotein E3, APOE epsilon 3, APOE epsilon3, Apo E 3, Apolipoprotein E 3, Apolipoprotein E epsilon3
Apolipoprotein E4 - 새창 A major and the second most common isoform of apolipoprotein E. In humans, Apo E4 differs from APOLIPOPROTEIN E3 at only one residue 112 (cysteine is replaced by arginine), and exhibits a lower resistance to denaturation and greater propensity to form folded intermediates. Apo E4 is a risk factor for ALZHEIMER DISEASE and CARDIOVASCULAR DISEASES.
Synonyms : Apo E epsilon 4, Apo E-4, Apo E4, ApoE4, Apolipoprotein E-4, Apo E 4, Apolipoprotein E 4