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  • apolipoprotein B-100
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  • apolipoprotein B-48
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  • apolipoprotein C
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  • apolipoprotein C-I
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  • apolipoprotein C-II
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APO abductor pollicis obliguus; acquired pendular oscillation; adriamycin, prednisone, vincristine; adve...
Apo, apo apolipoprotein
APOA, apoA apolipoprotein A
APOB, apoB apolipoprotein B
APOC, apoC apolipoprotein C
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APO E Apolipoprotein E
APO Apolipoprotein
APOE Apolipoprotein
a Apolipoprotein
Apo A Apolipoprotein A
CancerWEB ¿µ¿µ ÀÇÇлçÀü ¸ÂÃã °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
apolipoprotein <biochemistry, protein> The protein component of serum lipoproteins. Small proteins containing multiple copies of the kringle domain.
(18 Nov 1997)
apolipoprotein A-I <biochemistry> The major protein component of high density lipoproteins. It is instrumental in promoting efflux of cholesterol from extrahepatic tissue to the liver where it is metabolised and excreted from the body. The compound is the activator of lecithin-cholesterol acyltransferase which forms cholesteryl esters in hdl. The gene for this apolipoprotein is found on the long arm of chromosome 11.
(12 Dec 1998)
apolipoprotein A-II <biochemistry> A component of high density lipoproteins. It is instrumental in promoting efflux of cholesterol from extrahepatic tissue to the liver where it is metabolised and excreted from the body. This protein modulates the activation of lecithin-cholesterol acyltransferase in the presence of apolipoprotein A-I.
(12 Dec 1998)
apolipoprotein A-IV <biochemistry> An apolipoprotein secreted with chylomicrons.
(05 Mar 2000)
apolipoprotein B <biochemistry> Apolipoproteins found in LDL, VLDL, and IDL. Elevated in the plasma of individuals with familial hyperlipoproteinaemia.
(05 Mar 2000)
apolipoprotein B-100 <biochemistry> An apolipoprotein found in LDL, VLDL, and IDL. The ligand for the LDL receptor; absent in certain types of abetalipoproteinaemia.
Apolipoproteins are proteins on the surface of the lipoprotein complex that bind to specific enzymes or transport proteins across the cell membrane.
The normal range is 40 to 125 mg/dl.
Elevated levels may be seen in familial combined hyperlipidaemia and acquired hyperlipidaemia. Elevation may also be seen in cases of acute angina and myocardial infarction.
(27 Sep 1997)
apolipoprotein B-48 <biochemistry> An apolipoprotein found in chylomicrons and chylomicron remnants. Retained in intestine of individuals with chylomicron retention disease.
(05 Mar 2000)
apolipoprotein C-I <biochemistry> An apolipoprotein found in VLDL, HDL, and chylomicrons.
(05 Mar 2000)
apolipoprotein C-II <biochemistry> An apolipoprotein found in VLDL, HDL, and chylomicrons; an activator of lipoprotein lipase; a deficiency will result in accumulation of chylomicrons and triacylglycerols.
Apolipoproteins are proteins on the surface of the lipoprotein complex that bind to specific enzymes or transport proteins across the cell membrane.
Elevated levels may be seen in acute angina and acute myocardial infarction. Low levels are seen in apolipoprotein C-II deficiency. Normal levels are seen in type I hyperlipoproteinaemia.
(27 Sep 1997)
apolipoprotein C-III <biochemistry> An apolipoprotein found in VLDL, HDL, and chylomicrons.
(05 Mar 2000)
apolipoprotein D <biochemistry> An apolipoprotein found in HDL whose function is unclear.
(05 Mar 2000)
apolipoprotein E <biochemistry> An apolipoprotein found in VLDL, HDL, chylomicrons, and chylomicron remnants. Elevated in individuals with type III hyperlipoproteinaemia.
(05 Mar 2000)
apolipoprotein N-acyltransferase <enzyme> From e. Coli; catalyses the conversion of apolipoprotein to mature lipoprotein
Registry number: EC 2.3.1.-
Synonym: alp n-acyltransferase
(26 Jun 1999)
apolipoproteins The protein components of lipoproteins which remain after the lipids to which the proteins are bound have been removed. They play an important role in lipid transport and metabolism.
(12 Dec 1998)
apolipoproteins a Lipoproteins found in human blood serum in the high-density and very-high-density lipoprotein fraction (hdl, vhdl). They consist of several different polypeptides, the most important of which are apolipoprotein a-I and a-II. They maintain the structural integrity of the hdl particles and are activators of lecithin:cholesterol acyltransferase (lcat). Atherosclerotic patients show low apolipoprotein a levels and these apolipoproteins are either absent or present in extremely low plasma concentration in tangier disease.
(12 Dec 1998)
MeSH(Medical Subject Headings) ¸ÂÃã °Ë»ö (http://www.nlm.nih.gov) °á°ú : 5 ÆäÀÌÁö: 1
  • Apolipoprotein A-I - »õâ The most abundant protein component of HIGH DENSITY LIPOPROTEINS or HDL. This protein serves as an acceptor for CHOLESTEROL released from cells thus promoting efflux of cholesterol to HDL then to the LIVER for excretion from the body (reverse cholesterol transport). It also acts as a cofactor for LECITHIN CHOLESTEROL ACYLTRANSFERASE that forms CHOLESTEROL ESTERS on the HDL particles. Mutations of this gene APOA1 cause HDL deficiency, such as in FAMILIAL ALPHA LIPOPROTEIN DEFICIENCY DISEASE and in some patients with TANGIER DISEASE.
    Synonyms : Apo A-1, Apo A-I Isoproteins, Apo A1, Apo AI, ApoA-1, ApoA-I, Apolipoprotein A-1, Apolipoprotein A-I Isoprotein-2, Apolipoprotein A-I Isoprotein-4, Apolipoprotein A-I Isoproteins, Apolipoprotein A1, Apolipoprotein AI, Apolipoprotein AI Propeptide, Pro-Apo A-I
  • Apolipoprotein A-II - »õâ The second most abundant protein component of HIGH DENSITY LIPOPROTEINS or HDL. It has a high lipid affinity and is known to displace APOLIPOPROTEIN A-I from HDL particles and generates a stable HDL complex. ApoA-II can modulate the activation of LECITHIN CHOLESTEROL ACYLTRANSFERASE in the presence of APOLIPOPROTEIN A-I, thus affecting HDL metabolism.
    Synonyms : Apo A-2, Apo A-II Isoproteins, Apo A2, Apo AII, ApoA-2, ApoA-II, Apolipoprotein A-2, Apolipoprotein A-II Isoproteins, Apolipoprotein A2, Apolipoprotein AII, Pro-Apo A-II, Pro-Apolipoprotein A-II, Proapolipoprotein A-II, Apo A II Isoproteins, Apolipoprotein A 2
  • Apolipoprotein B-100 - »õâ A 513-kDa protein synthesized in the LIVER. It serves as the major structural protein of low-density lipoproteins (LIPOPROTEINS, LDL; LIPOPROTEINS, VLDL). It is the ligand for the LDL receptor (RECEPTORS, LDL) that promotes cellular binding and internalization of LDL particles.
    Synonyms : Apo B-100, Apo-B-100, ApoB-100, Apo B 100, ApoB 100, Apolipoprotein B 100
  • Apolipoprotein B-48 - »õâ A 241-kDa protein synthesized only in the INTESTINES. It serves as a structural protein of CHYLOMICRONS. Its exclusive association with chylomicron particles provides an indicator of intestinally derived lipoproteins in circulation. Apo B-48 is a shortened form of apo B-100 and lacks the LDL-receptor region.
    Synonyms : Apo B, Chylomicron, Apo B-48, ApoB-48, ApoB48, Apolipoprotein B, Chylomicron, Apolipoprotein B48, Apoprotein B-48, Chylomicron Apo B, Chylomicron Apolipoprotein B, Apo B 48, ApoB 48, Apolipoprotein B 48, Apoprotein B 48
  • Apolipoprotein C-I - »õâ A 6.6-kDa protein component of VERY-LOW-DENSITY LIPOPROTEINS; INTERMEDIATE-DENSITY LIPOPROTEINS; and HIGH-DENSITY LIPOPROTEINS. Apo C-I displaces APO E from lipoproteins, modulate their binding to receptors (RECEPTORS, LDL), and thereby decrease their clearance from plasma. Elevated Apo C-I levels are associated with HYPERLIPOPROTEINEMIA and ATHEROSCLEROSIS.
    Synonyms : Apo C-I, Apo C-I Precursor, Apolipoprotein C-I Precursor, Apolipoprotein C1, Pre Apo C-I, Apo C I, Apo C I Precursor, Apolipoprotein C I, Apolipoprotein C I Precursor, Pre Apo C I
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apolipoprotein E A protein whose main function is to transport cholesterol. The gene for this protein is on chromosome 19 and is referred to as APOE. There are three forms of APOE: e2, e3, and e4. APOE-e4 is associated with about 60 percent of late-onset Alzheimer
Ãâó: www.alz.org/Resources/Glossary.asp
apolipoprotein E Certain alleles of the gene which encodes the protein apolipoprotein E have been reported to be associated with the development of heart disease and Alzheimer's disease. Source : PhRMA Genomics
Ãâó: www.genomecanada.ca/GCglossaire/glossaire/index.as...
apolipoprotein E a gene situated on chromosome 19 that codes for a protein in lipoproteins that are normal constituents of blood plasma, for example HDL (high density lipoprotein), LDL (low density lipoprotein), and VLDL (very low density lipoprotein). There are a number of common variations (alleles) of the APOE gene, the most common of which are known as: e2, e3, and e4. Research has shown that people who inherit one or more copies of the APOEe4 gene are at increased risk of developing Alzheimer's disease. ...
Ãâó: www.medaus.com/p/147.html
apolipoprotein E A gene that codes for a protein in lipoproteins (complexes of fat + protein). The abbreviation for apolipoprotein E is ApoE.
Ãâó: www.memorydisorder.org/glossaryterms.htm
apolipoprotein Major protein component of lipoproteins; apolipoproteins have a variety of functions.
Ãâó: www.lipoprofile.com/control.cfm
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