| aortic valve insufficiency | Backflow of blood from the aorta into the left ventricle, owing to imperfect functioning of the aortic semilunar valve. (12 Dec 1998) |
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| aortic insufficiency | A congenital or acquired heart valve abnormality that results in the abnormal back flow of blood in the aorta, through an incompetent aortic valve and into the left ventricle. Chronic aortic insufficiency leads to enlargement of the left ventricle and pulmonary congestion. If left uncorrected, congestive heart failure will result. Aortic valve replacement is eventually necessary in most cases of significant valvular incompetence. (27 Sep 1997) |
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| mitral valve insufficiency | Backflow of blood from the left ventricle into the left atrium, owing to imperfect functioning of the mitral valve. (12 Dec 1998) |
| pulmonary valve insufficiency | Backflow of blood from the pulmonary artery into the right ventricle, owing to imperfect functioning of the pulmonary valve. (12 Dec 1998) |
| tricuspid valve insufficiency | Backflow of blood from the right ventricle into the right atrium, owing to imperfect functioning of the tricuspid valve. (12 Dec 1998) |
| aortic valve | The heart valve that divides the left ventricle and the aorta. The aortic valve opens during left ventricular contraction and then closes to prohibit the backwash of oxygenated blood from the aorta into the ventricle. The aortic valve has 3 valve cusps. (27 Sep 1997) |
| aortic valve prolapse | The downward displacement of the cuspal material (misalignment of the cusps) below a line joining points of attachment of the aortic valve leaflets. The prolapsed cusp may occlude the ventricular septal defect during ventricular diastole. (12 Dec 1998) |
| aortic valve stenosis | Narrowing of the orifice of the aortic valve or of the supravalular or subvalvular regions. (12 Dec 1998) |
| bicuspid aortic valve | See: familial aortic ectasia syndrome. (05 Mar 2000) |
| acute adrenocortical insufficiency | Severe adrenocortical insufficiency when an intercurrent illness or trauma causes an increased demand for adrenocortical hormones in a patient with adrenal insufficiency due to disease or use of relatively large amounts of similar hormones as therapy; characterised by nausea, vomiting, hypotension, and frequently hyperthemia, hyponatraemia, hyperkalaemia, and hypoglycaemia; can be fatal if untreated. Synonym: addisonian crisis, adrenal crisis, Bernard-Sergent syndrome. (05 Mar 2000) |
| adrenal gland insufficiency | <endocrinology> A condition that results from the inadequate production of adrenal hormones (see Addison's disease). (27 Sep 1997) |
| adrenal insufficiency | <endocrinology> A condition that results from the inadequate production of adrenal hormones (see Addison's disease). (27 Sep 1997) |
| adrenocortical insufficiency | Loss, to varying degrees, of adrenocortical function. Synonym: hypocorticoidism. (05 Mar 2000) |
| cardiac insufficiency | A condition where there is ineffective pumping of the heart leading to an accumulation of fluid in the lungs. Typical symptoms include shortness of breath with exertion, difficulty breathing when lying flat and leg or ankle swelling. Causes include chronic hypertension, cardiomyopathy and myocardial infarction. (27 Sep 1997) |
| valvular insufficiency | A leaky state of one or more of the cardiac valves, the valve not closing tightly and blood therefore regurgitating through it. Synonym: valvular incompetence, valvular insufficiency. (05 Mar 2000) |
| pancreatic insufficiency | Not enough of the digestive enzymes normally secreted by the pancreas into the intestine. Pancreatic insufficiency is a hallmark of cystic fibrosis. (12 Dec 1998) |