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antiport <cell biology, physiology> A membrane protein that transports two different ions or molecules, in opposite directions, across a lipid bilayer.
Energy may be required, as in the sodium pump or it may not, as in Na+/H+ antiport.
(13 Jan 1998)
antiporter A protein responsible for mediating the transport of two different molecules or ions simultaneously in opposite directions through a membrane.
(05 Mar 2000)
antiporters Membrane glycoproteins that transport substrates across the membrane in a tightly coupled stoichiometric manner. The stoichiometry of influx of one substrate and the efflux of another is fixed by a single transport catalytic cycle; that is, the membrane is not freely permeable to either substrate. Antiporters mediate secondary active transport, using the electrochemical energy of a primary gradient (mostly for sodium) that is built up by an ATP-consuming transporter (mostly sodium, potassium atpase) to maintain transmembrane gradients for other electrolytes or metabolic substrates.
(12 Dec 1998)
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