| antimetabolite | <pharmacology> A group of anti-cancer drugs which prevent cells growing and dividing by blocking the chemical reactions required in the dividing by blocking the chemical reactions required in the cell to produce DNA. Drugs of this type include 6 mercaptopurine, azathioprine, thioguanine, methotrexate. See: chemotherapy. (13 Oct 1997) |
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| antimetabolites | Drugs that are chemically similar to naturally occurring metabolites, but differ enough to interfere with normal metabolic pathways. (12 Dec 1998) |
| antimetabolites, antineoplastic | Antimetabolites that are useful in cancer chemotherapy. (12 Dec 1998) |