| AFP | Alpha(¥á) Feto-Protein [HP 1826, 1858, 1859, 2265] ; Oncofetal Antigens &nbs... |
|---|---|
| Anti-ENA | Anti-Extractable Nuclear Antigens |
| CEA | Carcino-Embryonic Antigen [HP 1825-6] ; Oncofetal Antigens ; Glycopro... |
| CREG | Cross REactive Group (of HLA Antigens) |
| ANA | acetylneuraminic acid; American Narcolepsy Association; American Neurological Association; American ... |
| HLA | Histocompatibility Antigens |
|---|---|
| Ipa | Invasion plasmid antigens |
| MHC | Major histocompatibility antigens |
| MAA | Melanoma-associated antigens |
| MiHA | Minor histocompatibility antigens |
| antigens | Substances which are capable, under appropriate conditions, of inducing a specific immune response and of reacting with the products of that response, that is, with specific antibodies or specifically sensitised T-lymphocytes, or both. Antigens may be soluble substances, such as toxins and foreign proteins, or particulates, such as bacteria and tissue cells; however, only the portion of the protein or polysaccharide molecule known as the antigenic determinant (epitopes) combines with antibody or a specific receptor on a lymphocyte. (12 Dec 1998) |
|---|---|
| antigens, archaeal | Substances of archaeal origin that have antigenic activity. (12 Dec 1998) |
| antigens, bacterial | Substances elaborated by bacteria that have antigenic activity. (12 Dec 1998) |
| antigens, CD | <immunology> Differentiation antigens residing on human leukocytes. CD stands for cluster of differentiation, which refers to groups of monoclonal antibodies that show similiar reactivity with certain subpopulations of antigens. The subpopulations of antigens are also known by the same CD designation. (12 Dec 1998) |
| antigens, CD1 | <immunology> Glycoproteins expressed on cortical thymocytes and on some dendritic cells and B-cells. Their structure is similar to that of MHC class I and their function has been postulated as similar also. Cd1 antigens are highly specific markers for human langerhans cells. (12 Dec 1998) |
| antigens, CD11 | <immunology> A group of three different alpha chains (CD11a, CD11b, CD11c) that are associated with an invariant CD18 beta chain (antigens, CD18). The three resulting leukocyte-adhesion molecules (receptors, leukocyte adhesion) are lymphocyte function-associated antigen-1, macrophage-1 antigen, and antigen, p150,95. (12 Dec 1998) |
| antigens, CD13 | <enzyme, immunology> Glycoproteins expressed on human granulocyte-monocyte progenitor colony forming units (cfu-gm) and their more differentiated progeny. The enzymes are also found in a large number of tissues, often associated with membranes. Registry number: EC 3.4.11.2 (12 Dec 1998) |
| antigens, CD14 | <immunology> Glycolipid-anchored membrane glycoproteins expressed on cells of the myelomonocyte lineage including monocytes, macrophages, and some granulocytes. They function as receptors for the complex of lipopolysaccharide (lps) and lps-binding protein. (12 Dec 1998) |
| antigens, CD15 | <immunology> Carbohydrate antigen which is accumulated in various human cancer tissues and secreted into the blood stream. The carbohydrate moiety can be further modified with fucose or sialic acid. Monoclonal antibodies have been determined which can discriminate each subgroup of this antigen in the sera of cancer patients. Sialyl ssea-1 antigen is particularly elevated in the sera of patients with a variety of tumours. (12 Dec 1998) |
| antigens, CD18 | <immunology> Cell-surface glycoprotein beta-chains that are non-covalently linked to specific alpha-chains of the CD11 family of leukocyte-adhesion molecules (receptors, leukocyte-adhesion). A defect in the gene encoding CD18 causes leukocyte-adhesion deficiency syndrome. (12 Dec 1998) |
| antigens, CD19 | <immunology> Differentiation antigens expressed on B-lymphocytes and B-cell precursors. They are involved in regulation of B-cell proliferation. (12 Dec 1998) |
| antigens, CD2 | <immunology> Glycoprotein members of the immunoglobulin superfamily which participate in T-cell adhesion and activation. They are expressed on most peripheral T-lymphocytes, natural killer cells, and thymocytes, and function as co-receptors or accessory molecules in the T-cell receptor complex. (12 Dec 1998) |
| antigens, CD20 | <immunology> Unglycosylated phosphoproteins expressed only on B-cells. They are regulators of transmembrane calcium conductance and thought to play a role in B-cell activation and proliferation. (12 Dec 1998) |
| antigens, CD26 | <enzyme, immunology> Cell-surface glycoproteins and serine protease, also known as dipeptidyl-peptidase IV, that play a role in t-lymphocyte activation. Cd26 binds to adenosine deaminase on the T-cell surface. Registry number: EC 3.4.14.5 (12 Dec 1998) |
| antigens, CD27 | <immunology> Dimeric membrane glycoproteins found on most T-lymphocytes. Activation of T-cells by the antigen receptor increases CD27 surface expression. (12 Dec 1998) |
| ABO antigens | <haematology, immunology> A system of genetically determined antigens (proteins) located on the surface of the erythrocyte. The presence of these specific antigens gives a blood its unique properties. Because of the antigen differences existing between individuals, blood groups are significant in blood transfusions, maternal-foetal incompatibilities (erythroblastosis foetalis), tissue and organ transplantation. (27 Sep 1997) |
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| Am antigens | Allotypic determinants (antigens) on human immunoglobulin alpha heavy chains. (05 Mar 2000) |
| CDE antigens | rh blood group |
| CENP antigens | <molecular biology> Proteins of the kinetochore (CENP A 27 kD, CENP B 80 kD, CENP C 140 kD and CENP D 50 kD) that react strongly with antibodies from CREST sera. (18 Nov 1997) |
| Gm antigens | Allotypic determinants (antigens) that are present on the heavy chain of immunoglobulin G. There are 25 different determinants present throughout the human population. (05 Mar 2000) |
| Rh antigens | rh blood group |
| group antigens | Antigen's that are shared by related genera of microorganisms. (05 Mar 2000) |
| class I antigens | Cell membrane bound glycoproteins that are coded by genes of the major histocompatibility complex. (05 Mar 2000) |
| class II antigens | A cell membrane glycoprotein encoded by genes of the major histocompatibility complex. These antigens are distributed on antigen-presenting cells such as macrophages, B-cells, and dendritic cells. (05 Mar 2000) |
| class III antigens | Non-cell membrane molecules that are encoded by the S region of the major histocompatibility complex. These antigens are not involved in determining histocompatibility and include the complement proteins. (05 Mar 2000) |
| minor histocompatibility antigens | Allelic alloantigens often responsible for weak graft rejection in cases when (major) histocompatibility has been established by standard tests. In the mouse they are coded by more than 500 genes at up to 30 minor histocompatibility loci. The most well-known minor histocompatibility antigen in mammals is the h-y antigen. (12 Dec 1998) |
| minor lymphocyte stimulatory antigens | Endogenous superantigens responsible for inducing strong proliferative responses in T-cells in mixed lymphocyte reactions (see mixed lymphocyte culture test). They are encoded by mouse mammary tumour viruses that have integrated into the germ line as DNA proviruses (minor lymphocyte stimulatory loci). (12 Dec 1998) |
| MN blood group antigens | <haematology, immunology> A pair of blood group antigens governed by genes that segregate independently of the ABO locus. The alleles are codominant and there are three types MM, NN and MN. Glycophorin has M or N activity and this is associated with oligosaccharides attached to the amino terminal portion of the molecule. M type glycophorin differs from N type in amino acid residues 1 and 5, although the antigenic determinants are associated with the carbohydrate side chains. (18 Nov 1997) |
| hepatitis antigens | Antigens from any of the hepatitis viruses including surface, core, and other associated antigens. (12 Dec 1998) |
| hepatitis b e antigens | A closely related group of antigens found in the plasma only during the infective phase of hepatitis b or in virulent chronic hepatitis b, probably indicating active virus replication; there are three subtypes which may exist in a complex with immunoglobulins g. (12 Dec 1998) |
Synonyms : Antigen
Synonyms :
Synonyms :
Synonyms : CD Antigens
Synonyms : CD1 Antigen, Antigen, CD1
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