| rodenticide | <chemistry> Any chemical used to kill rodents (rats, mice, etc.) (17 Dec 1997) |
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| anticoagulant | <haematology, pharmacology> Any substance that prevents blood clotting. Those drugs administered for prophylaxis or treatment of thromboembolic disorders are heparin, which inactivates thrombin and several other clotting factors and which must be administered parenterally and the oral anticoagulants (warfarin, dicumarol and congeners) which inhibit the hepatic synthesis of vitamin K dependent clotting factors. Anticoagulant solutions used for the preservation of stored whole blood and blood fractions are acid citrate dextrose (ACD), citrate phosphate dextrose (CPD), citrate phosphate dextrose adenine (cPDA 1) and heparin. Anticoagulants used to prevent clotting of blood specimens for laboratory analysis are heparin and several substances that make calcium ions unavailable to the clotting process, including EDTA (ethylenediaminetetraacetic acid), citrate, oxalate and fluoride. (18 Nov 1997) |
| anticoagulant therapy | The use of anticoagulant drugs to reduce or prevent intravascular or intracardiac clotting. (05 Mar 2000) |
| vascular anticoagulant | <protein> Group of calcium-binding proteins that interact with acidic membrane phospholipids in membranes. They contain 4 or 8 repeats of a 61 amino acid domain that folds into 5 a helices. Also known by several other names (e.g. Lipocortins, endonexins), reflecting the history of their discovery in different contexts. See: lipocortin, endonexin I & II, calpactin, p70 and calelectrin. (18 Nov 1997) |
| lupus anticoagulant | An immunoglobulin that interferes with blood coagulation and has antithromboplastin activity. This immunoglobulin can prolong blood clotting and occurs in approximately 25% of people with lupus. (27 Sep 1997) |