| 영문 | antibiotics | 한글 | 항생제 |
|---|---|---|---|
| 설명 | 미생물이 만들어내는 항생 물질로 된 약제. 다른 미생물이나 생물 세포를 선택적으로 억제하거나 죽인다. 미생물에 의해 생산되며 미생물의 발육 또는 악성종양의 증식을 저지하는 물질이다. 숙주에 무해한 항생물질은 사람-동물-식물의 세균감염증의 치료에 화학요법제로 사용한다. 그 작용메커니즘은 미생물의 세포벽을 합성하는 것을 저해하는 것, 핵산(DNA, RNA) 합성저해, 단백질 합성저해, 보효소합성저해 등이 있다. 작용메커니즘과 화학구조에 따라 β-락탐계(페니실린류), 아미노당류계, 테트라사이클린계, 클로람페니콜계, 폴리펩티드계, 기타(린코마이신, 반코마이신 등)로 분류된다. 항종양항생물질에는 아드리아마이신, 악티노마이신D, 마이토마이신C, 블레오마이신 등이 있다. |
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| APH | alcohol-positive history; alternative pathway hemolysis; aminoglycoside phosphotransferase; antepart... |
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| MARSA | methicillin-aminoglycoside-resistant Staphylococcus aureus |
| TEF | Tracheo-Esophageal Fistula ? Tx 1. Infant Warmer ... |
| NOABX | no antibiotics |
| ORALABX | oral antibiotics |
| AGs | Aminoglycoside antibiotics |
|---|---|
| AB | Antibiotics |
| AG | Aminoglycoside |
| APHs | Aminoglycoside phosphotransferases |
PDGF (혈소판 유래 성장 인자
| antibiotics, aminoglycoside | Antibiotics whose structure contains amino sugars attached to an aminocyclitol ring (hexose nucleus) by glycosidic bonds. Aminoglycoside antibiotics are derived from various species of streptomyces and micromonospora or are produced synthetically. They act by inhibiting protein synthesis. (12 Dec 1998) |
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| 6'-aminoglycoside acetyltransferase-2''-aminoglycoside phosphotransferase | <enzyme> Bifunctional enzyme which confers resistance to aminoglycoside antibiotic including gentamicin, tobramycin and amikacin; type aph(2'') with two apostrophes, not quotes Registry number: EC 2.- Synonym: aac(6')-aph(2'') (26 Jun 1999) |
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| aminoglycoside | <pharmacology> A group of antibiotics active against many aerobic gram-negative and some gram-positive bacteria. They are mostly produced by fungi and contain an amino sugar, and amino-or guanido-substituted inositol ring which are attached by a glycosidic linkage to a hexose nucleus resulting in a polycationic and highly polar compound. They inhibit bacterial protein synthesis by binding to a site on the 30S ribosomal subunit thereby altering codon anticodon recognition. They are all broad-spectrum antibiotics and can cause renal toxicity and ototoxicity. Common examples are streptomycin, gentamicin, amikacin, kanamycin, tobramycin, netilmicin, neomycin, framycetin. (13 Oct 1997) |
| aminoglycoside 3'-phosphotransferase | <enzyme> A bacterial enzyme which confers resistance to the antibiotic neomycin.The APH gene is used as a selectable marker in genetic experiments, whereby bacterial cells which do not have the gene are eliminated from a population and thus selected against when exposed to neomycin. (13 Oct 1997) |
| aminoglycoside 6-adenylyltransferase | <enzyme> From bacillus subtilis marburg Registry number: EC 2.7.7.- Synonym: aminoglycoside 6-adenyltransferase, ag-6-atransferase (26 Jun 1999) |
| aminoglycoside acetyltransferase | <enzyme> See also gentamicin acetyltransferase Registry number: EC 2.3.1.- Synonym: aminocyclitol acetyltransferase, neomycin acetyltransferase (26 Jun 1999) |
| aminoglycoside N1-acetyltransferase | <enzyme> Monoacetylates apramycin, butirosin, lividomycin and paromomycin at the c1 amino group and diacetylates ribostamycin and neomycin, at the c1 amino and possibly at the 6' amino group Registry number: EC 2.3.1.- Synonym: acc1 enzyme, paromomycin acetyltransferase (26 Jun 1999) |
| aminoglycoside N(3')-acetyltransferase | <enzyme> Catalyses the reaction of CoA and acetyl-2-deoxystreptamine antibiotic to yield acetyl-CoA and a 2-deoxystreptamine antibiotic; has broad specificity; acts on gentamicin, tobramycin, sisomicin, netilmicin, kanamycin, neomycin and apramycin Registry number: EC 2.3.1.81 Synonym: aac(3)-iv, aminoglycoside-(3)-n-acetyltransferase iv (26 Jun 1999) |
| aminoglycoside N(6')-acetyltransferase | <enzyme> The antibiotic kanamycin, gentamicin, tobramycin, and neomycin can act as an acceptor; has to be 6'-acetyltransferase Registry number: EC 2.3.1.82 Synonym: amikacin acetyltransferase, aminoglycoside-6'-n-acetyltransferase, gentamicin 6'-acetyltransferase, 6' gat gene product, aac(6') (26 Jun 1999) |
| aminoglycoside phosphoribosyltransferase | <enzyme> Coded by neo-gene; involved in kanamycin resistance; no other information given on reaction 8/93 Registry number: EC 2.4.2.- Synonym: aminoglycosidephosphoribosyltransferase (26 Jun 1999) |
| antibiotics | Drugs that fight infections. (12 Dec 1998) |
| antibiotics, anthracycline | Antibiotics which have a tetrahydronaphthacenedione ring structure attached by a glycosidic linkage to a sugar molecule. These antibiotics have potent antineoplastic activity. The two best known members of this group are daunorubicin and doxorubicin. Since these agents intercalate with DNA, many DNA functions are adversely affected. Futhermore they interact with cell membranes thereby altering their functions and also generate hydrogen peroxide and hydroxy radicals which are highly destructive to cells. (12 Dec 1998) |
| antibiotics, antifungal | Antibiotics inhibiting the growth of or killing fungi and used in the treatment of various fungal diseases. (12 Dec 1998) |
| antibiotics, antineoplastic | Chemical substances, produced by microorganisms, inhibiting or preventing the development of neoplasms. (12 Dec 1998) |
| antibiotics, antitubercular | Substances obtained from various species of microorganisms that are, alone or in combination with other agents, of use in treating various forms of tuberculosis; most of these agents are merely bacteriostatic, induce resistance in the organisms, and may be toxic. (12 Dec 1998) |
| antibiotics, combined | Combination of antibiotics used against difficult-to-treat infections. Antibiotic combinations have been used mainly to broaden the antibacterial spectrum and prevent development of resistance. In some instances these combinations have shown lower toxicity, but drug antagonism may be one of the problems encountered by their use. They may be given simultaneously or sequentially. The drugs need not be in the same dosage form. (12 Dec 1998) |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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