| anti-idiotype autoantibody | <immunology> An autoantibody, the specificity of which is directed against one of one's own idiotypes. See: anti-idiotype antibody. Synonym: idiotype autoantibody. (05 Mar 2000) |
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| autoantibody | Antibody that reacts with an antigen that is a normal component of the body. Obviously this can lead to some problems and autoimmunity has been proposed as a causative factor in a number of diseases such as rheumatoid arthritis. See: systemic lupus erythematosus, Hashimoto's thyroiditis, myasthenia gravis. (18 Nov 1997) |
| warm autoantibody | An autoantibody that reacts optimally at 37캜. (05 Mar 2000) |
| cold autoantibody | An autoantibody that reacts at temperatures below 37캽. (05 Mar 2000) |
| haemagglutinating cold autoantibody | A cold autoagglutinin. (05 Mar 2000) |
| Donath-Landsteiner cold autoantibody | An autoantibody of the IgG class responsible for paroxysmal cold haemoglobinuria; it is adsorbed to red cells only at temperatures of 20캜 or lower, causing the red cells to lyse in the presence of complement at higher temperatures; it has only slight agglutinating properties in spite of its marked lytic activity, and has a specificity within the blood group P; it is also occasionally present for short periods of time following measles and other infections, and formerly was frequently associated with syphilis. Synonym: cold haemolysin. (05 Mar 2000) |
| idiotype autoantibody | <immunology> An autoantibody, the specificity of which is directed against one of one's own idiotypes. See: anti-idiotype antibody. Synonym: idiotype autoantibody. (05 Mar 2000) |