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annealing 1. Toughening upon slow cooling.
2. Used in the context of DNA renaturation after temperature dissociation of the two strands. Rate of annealing is a function of complementarity.
3. Fusion of microtubules or microfilaments end to end.
(18 Nov 1997)
annealing lamp An alcohol lamp with a soot-free flame used in dentistry to drive off the protective NH3 gas coating from the surface of cohesive gold foil.
(05 Mar 2000)
simulated annealing <molecular biology> In the biosciences, this refers to using computers to model how complementary strands of DNA or RNA will link via hydrogen bonds to form a double-stranded molecule, or how a protein sequence will fold up and make hydrogen bonds with itself to form a more convoluted molecule.
(09 Oct 1997)
DNA annealing <molecular biology> The reformation of double stranded DNA from thermally denatured DNA. The rate of reassociation depends upon the degree of repetition and is slowest for unique sequences (this is the basis of the Cot value).
(18 Nov 1997)
absolute temperature Temperature reckoned in Kelvins from absolute zero.
(05 Mar 2000)
basal body temperature <biology> The temperature taken at its lowest point in the day, usually in the morning before getting out of bed.
(09 Oct 1997)
body temperature changes Any deviation from normal body temperature of the human body, about 98.6 degrees f. Or 37 degrees c. When taken orally.
(12 Dec 1998)
maximum temperature In bacteriology, denoting a temperature above which growth will not take place.
(05 Mar 2000)
mean temperature The average atmospheric temperature in any locality for a designated period of time, as a month or a year.
(05 Mar 2000)
restrictive temperature <molecular biology> Of a temperature sensitive mutation, a temperature at which the mutated gene product behaves normally and so the cell or organism survives as if wild type. C.f. The restrictive temperature, at which the gene product takes on a mutant phenotype.
(18 Nov 1997)
melting temperature The midpoint in the change in optical properties (absorbance, rotation) of a structured polymer (e.g., DNA) with increasing temperature.
Synonym: melting temperature.
(05 Mar 2000)
melting temperature of DNA That temperature at which, under a given set of conditions, double-stranded DNA is changed (50%) to single-stranded DNA; under standard conditions, the base composition of the DNA can be estimated from the denaturation temperature, since the greater the denaturation temperature, the greater the guanine-plus-cytosine content (i.e., GC content) of the DNA.
Synonym: melting temperature of DNA.
(05 Mar 2000)
permissive temperature <molecular biology> Of a temperature sensitive mutation, a temperature at which the mutated gene product behaves normally and so the cell or organism survives as if wild type. C.f. The restrictive temperature, at which the gene product takes on a mutant phenotype.
(18 Nov 1997)
room temperature The ordinary temperature (65
minimum temperature In bacteriology, denoting a temperature below which growth will not take place.
(05 Mar 2000)
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