| pain insensitivity, congenital | Absence of sensibility to pain or inability to feel pain. The condition is present at birth. (12 Dec 1998) |
|---|---|
| congenital insensitivity to pain | <radiology> Autosomal recessive, neuropathic joints, micro- and macrofractures, epiphyseal separation, osteomyelitis (mandible, fingers, toes) Differential diagnosis: congenital insensitivity to pain with anhidrosis (autosomal recessive), hereditary sensory radicular neuropathy (autosomal recessive), congenital sensory neuropathy (autosomal dominant), familial dysautonomia (autosomal recessive), Lesch-Nyhan syndrome (X recessive) (12 Dec 1998) |
| adrenal androgen | Any androgenic hormone of adrenocortical origin; e.g., dehydroepiandrosterone (and its sulfate), androstenedione, 11b-hydroxyandrostenedione. (05 Mar 2000) |
| adrenal androgen-stimulating hormone | A putative pituitary hormone that may be responsible for increased secretion of adrenal androgens at the time of puberty. (05 Mar 2000) |
| androgen | <endocrinology> General term for any male sex hormone in vertebrates. Androgens may be used in patients with breast cancer to treat recurrence of the disease. (14 May 1997) |
| androgen antagonists | Compounds which inhibit or antagonise the biosynthesis or actions of androgens. (12 Dec 1998) |
| androgen binding protein | A protein secreted by testicular Sertoli cells along with inhibin and mullerian inhibiting substance. Androgen binding protein probably maintains a high concentration of androgen in the seminiferous tubules. (05 Mar 2000) |
| androgen-binding proteins | Carrier proteins produced in the sertoli cells of the testis, secreted into the seminiferous tubules, and transported via the efferent ducts to the epididymis. Participate in the transport of androgens; include also synthetic androgens binding proteins. (12 Dec 1998) |
| androgen-dependent secretory protease | <enzyme> Glycoprotein from dog prostate; hydrolyzes arginine and lysine-containing amide and ester protease substrates Registry number: EC 3.4.99.- Synonym: ads-protease (26 Jun 1999) |
| androgen resistance syndromes | A class of disorders associated with 5a-steroid reductase deficiency, testicular feminization, and related disorders. Compare: steroid 5a-reductase, Reifenstein's syndrome, infertile male syndrome, testicular feminization syndrome. (05 Mar 2000) |
| androgen unit | The androgenic activity of 100 ug (0.1 mg) of crystalline androsterone as assayed by the comb growth response in capons. (05 Mar 2000) |
| receptors, androgen | Proteins, generally found in the cytoplasm, that specifically bind androgens and mediate their cellular actions. The complex of the androgen and receptor migrates to the nucleus where it induces transcription of specific segments of DNA. (12 Dec 1998) |