| ancrod | <enzyme> An enzyme fraction from the venom of the malayan pit viper, agkistrodon rhodostoma. It catalyses the hydrolysis of a number of amino acid esters and a limited proteolysis of fibrinogen. It is used clinically to produce controlled defibrination in patients requiring anticoagulant therapy. Pharmacological action: anticoagulant, fibrinolytic agent. Registry number: EC 3.4.21.28 (12 Dec 1998) |
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Synonyms : Arvin, Arvin IRC-50, Arwin, Berk Brand of Ancrod, Knoll Brand of Ancrod, Venacil, Ancrod Berk Brand, Ancrod Knoll Brand, Arvin IRC 50, Arvin IRC50
| ancrod |
a proteinase obtained from the venom of the Malayan pit viper Agkistrodon rhodostoma; it reduces the blood concentration of fibrinogen and is used as an anticoagulant in the treatment of deep venous thrombosis and the prevention of postoperative thrombosis.
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