amyloid beta-protein : KMLE 의학 검색 엔진 - 의학사전, 의학용어, 의학약어, 의학논문, 약품/의약품 검색

MeSH(Medical Subject Headings) 맞춤 검색 (http://www.nlm.nih.gov) 결과 : 2 페이지: 1

Amyloid beta-Protein - 새창 A 4-kDa protein, 39-43 amino acids long, expressed by a gene located on chromosome 21. It is the major protein subunit of the vascular and plaque amyloid filaments in individuals with Alzheimer's disease and in aged individuals with trisomy 21 (DOWN SYNDROME). The protein is found predominantly in the nervous system, but there have been reports of its presence in non-neural tissue.
Synonyms : ABP (Alzheimer's), Amyloid AD-AP, AD-AP, Amyloid, Alzheimer beta Protein, Amyloid AD AP, Amyloid beta Protein, Protein A4, Amyloid, Protein, beta-Amyloid, beta Amyloid Protein, beta-Protein, Alzheimer, beta-Protein, Amyloid
Amyloid beta-Protein Precursor - 새창 A precursor to the AMYLOID-BETA PROTEIN (beta/A4). Alterations in the expression of the amyloid beta-protein precursor (ABPP) gene, located on chromosome 21, plays a role in the development of the neuropathology common to both ALZHEIMER DISEASE and DOWN SYNDROME. ABPP is associated with the extensive extracellular matrix secreted by neuronal cells. Upon cleavage, this precursor produces three proteins of varying amino acid lengths: 695, 751, and 770. The beta/A4 (695 amino acids) or beta-amyloid protein is the principal component of the extracellular amyloid in senile plaques found in ALZHEIMER DISEASE; DOWN SYNDROME and, to a limited extent, in normal aging.
Synonyms : Amyloid beta Precursor Protein, Amyloid beta Protein Precursor, beta Amyloid Protein Precursor, beta-Protein Precursor, Amyloid