amyloid : KMLE 의학 검색 엔진 - 의학사전, 의학용어, 의학약어, 의학논문, 약품/의약품 검색

MeSH(Medical Subject Headings) 맞춤 검색 (http://www.nlm.nih.gov) 결과 : 5 페이지: 1

Amyloid - 새창 A type of extracellularly deposited substance composed of an amyloid protein and additional components including HEPARAN SULFATE PROTEOGLYCAN; LAMININ; COLLAGEN TYPE IV; SERUM AMYLOID P-COMPONENT; and APOLIPOPROTEINS E which together form characteristic amyloid fibrils. The core of amyloid fibrils is formed by the stacking of overlapping beta-pleated sheet domains of the amyloid protein. There are many different amyloid proteins that have been found forming the core of the fibrils in vivo. However, amyloid can be formed from any protein that exposes beta-pleated strand conformations during unfolding or refolding. A common characteristic of amyloid is the ability to bind such dyes as CONGO RED and thioflavine.
Synonyms : Amyloid Fibrils, Amyloid Proteins, Amyloid Substance, Fibrils, Amyloid, Proteins, Amyloid, Substance, Amyloid
Amyloid beta-Protein - 새창 A 4-kDa protein, 39-43 amino acids long, expressed by a gene located on chromosome 21. It is the major protein subunit of the vascular and plaque amyloid filaments in individuals with Alzheimer's disease and in aged individuals with trisomy 21 (DOWN SYNDROME). The protein is found predominantly in the nervous system, but there have been reports of its presence in non-neural tissue.
Synonyms : ABP (Alzheimer's), Amyloid AD-AP, AD-AP, Amyloid, Alzheimer beta Protein, Amyloid AD AP, Amyloid beta Protein, Protein A4, Amyloid, Protein, beta-Amyloid, beta Amyloid Protein, beta-Protein, Alzheimer, beta-Protein, Amyloid
Amyloid beta-Protein Precursor - 새창 A precursor to the AMYLOID-BETA PROTEIN (beta/A4). Alterations in the expression of the amyloid beta-protein precursor (ABPP) gene, located on chromosome 21, plays a role in the development of the neuropathology common to both ALZHEIMER DISEASE and DOWN SYNDROME. ABPP is associated with the extensive extracellular matrix secreted by neuronal cells. Upon cleavage, this precursor produces three proteins of varying amino acid lengths: 695, 751, and 770. The beta/A4 (695 amino acids) or beta-amyloid protein is the principal component of the extracellular amyloid in senile plaques found in ALZHEIMER DISEASE; DOWN SYNDROME and, to a limited extent, in normal aging.
Synonyms : Amyloid beta Precursor Protein, Amyloid beta Protein Precursor, beta Amyloid Protein Precursor, beta-Protein Precursor, Amyloid
Amyloid Neuropathies - 새창 Disorders of the peripheral nervous system associated with the deposition of AMYLOID in nerve tissue. Familial, primary (nonfamilial), and secondary forms have been described. Some familial subtypes demonstrate an autosomal dominant pattern of inheritance. Clinical manifestations include sensory loss, mild weakness, autonomic dysfunction, and CARPAL TUNNEL SYNDROME. (Adams et al., Principles of Neurology, 6th ed, p1349)
Synonyms : Amyloid Neuropathy, Secondary, Amyloid Polyneuropathies, Amyloid Neuropathies, Secondary, Amyloid Neuropathy, Amyloid Polyneuropathy, Neuropathies, Secondary Amyloid, Neuropathy, Amyloid, Neuropathy, Secondary Amyloid, Polyneuropathies, Amyloid
Amyloid Neuropathies, Familial - 새창 Inherited disorders of the peripheral nervous system associated with the deposition of AMYLOID in nerve tissue. The different clinical types based on symptoms correspond to the presence of a variety of mutations in several different proteins including transthyretin (PREALBUMIN); APOLIPOPROTEIN A-I; and GELSOLIN.
Synonyms : Amyloid Polyneuropathy, British Type, Amyloid Polyneuropathy, Iowa Type, Amyloid Polyneuropathy, Swiss Type, Appalachian Type Familial Amyloid Polyneuropathy, British Type Amyloid Polyneuropathy, Familial Amyloid Neuropathy, Andrade Type