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amylase-creatinine clearance ratio A test for the diagnosis of acute pancreatitis; it is determined by measuring amylase and creatinine in serum and urine in apparently healthy individuals the renal clearance of amylase is less than 5% that of creatinine; in acute pancreatitis the ratio is said to be greater than 0.05 or 5%.
(05 Mar 2000)
alpha-amylase <enzyme> An enzyme that catalyses the endohydrolysis of 1,4-alpha-glycosidic linkages in starch, glycogen, and related polysaccharides and oligosaccharides containing 3 or more 1,4-alpha-linked d-glucose units.
Pharmacological action: anti-inflammatory agents.
Chemical name: 1,4-alpha-D-Glucan glucanohydrolase
Registry number: EC 3.2.1.1
(12 Dec 1998)
amylase <enzyme> An enzyme produced in the pancreas and salivary glands. Elevation of the blood amylase is common in conditions of pancreatitis.
(27 Sep 1997)
beta-amylase <enzyme> An enzyme that catalyses the hydrolysis of 1,4-alpha-glycosidic linkages in starch, glycogen, and related polysaccharides and oligosaccharides so as to remove successive beta-maltose units from the non-reducing ends of the chains.
Chemical name: 1,4-alpha-D-Glucan maltohydrolase
Registry number: EC 3.2.1.2
(12 Dec 1998)
gamma-amylase A hydrolase removing terminal alpha-1,4-linked d-glucose residues from nonreducing ends of chains, with release of beta-d-glucose.
Synonym: acid maltase, amyloglucosidase, gamma-amylase, glucoamylase.
(05 Mar 2000)
maltotriose-forming amylase <enzyme> Also carries out transglycosylation, forming p-nitrophenyl alpha-maltotetraoside from maltotetraose and p-nitrophenyl alpha-d-glucopyranoside
Registry number: EC 3.2.1.-
Synonym: g3-amylase
(26 Jun 1999)
glycosylated alpha-amylase <enzyme> Contains a single biantennary n-linked oligosaccharide that terminates with the structure fucalpha1,3(galbeta1,4)glcnac
Registry number: EC 3.2.1.-
Synonym: human glycosylated alpha-amylase
(26 Jun 1999)
saccharogen amylase <enzyme> An enzyme that catalyses the hydrolysis of 1,4-alpha-glycosidic linkages in starch, glycogen, and related polysaccharides and oligosaccharides so as to remove successive beta-maltose units from the non-reducing ends of the chains.
Chemical name: 1,4-alpha-D-Glucan maltohydrolase
Registry number: EC 3.2.1.2
(12 Dec 1998)
ANP clearance receptors Cell surface proteins that bind atrial natriuretic peptide and ANP fragments without initiating biological action.
(05 Mar 2000)
p-aminohippurate clearance A good measure of renal plasma flow, which it slightly underestimates; when a low plasma concentration of p-aminohippurate (PAH) is maintained by intravenous infusion, the kidney extracts and excretes almost all of the PAH from the plasma before it reaches the renal vein.
(05 Mar 2000)
maximum urea clearance The urea clearance when the urine flow exceeds 2 ml/min; normal value is about 75 ml blood/min per 1.73 m2 body surface area.
(05 Mar 2000)
metabolic clearance rate Volume of biological fluid completely cleared of drug metabolites as measured in unit time. Elimination occurs as a result of metabolic processes in the kidney, liver, saliva, sweat, intestine, heart, brain, or other site.
(12 Dec 1998)
clearance 1. The process of clearing.
2. <physiology> The rate at which a substance is removed from the blood.
(18 Nov 1997)
mucociliary clearance Rate of ciliary and secretory activity of the respiratory submucosal glands. It is a non-specific host defense mechanism, measurable in vivo by mucus transfer, ciliary beat frequency, and clearance of radioactive tracers.
(12 Dec 1998)
creatinine clearance Measurement of the clearance of endogenous creatinine, used for evaluating the glomerular filtration rate (GFR).
(05 Mar 2000)
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