| attenuation | <radiobiology> Process by which a beam of radiation is reduced in intensity when passing through material - combination of absorption and scattering processes, leading to a decrease in flux density of beam when projected through matter. (16 Dec 1997) |
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| attenuation coefficient | 1. <radiobiology> Compton: The fractional number of photons removed from a beam of radiation per unit thickness of material through which it is passing as a result of Compton effect interactions. 2. Linear: The fractional number of photons removed from a beam of radiation per unit thickness of material through which it is passing due to all absorption and scattering processes. 3. Pair Production: That fractional decrease in the intensity of a beam of ionising radiation due to pair production in a medium through which it passes. 4. Photoelectric Effect: That fractional decrease in the intensity of a beam of ionising radiation due to photoelectric effect in a medium through which it passes. (16 Dec 1997) |
| attenuation compensation | In ultrasonography, an increase in receiver gain with time to compensate for loss in echo amplitude with depth, usually due to attenuation. Synonym: attenuation compensation, depth compensation, time compensation gain, time-compensated gain, time-varied gain control, time-varied gain. (05 Mar 2000) |
| attenuation factor | <radiobiology> A measure of the opacity of a layer of material for radiation transversing it, the ratio of the incident intensity to the transmitted intensity. It is equal to Io/I, where Io and I are the intensities of the incident and emergent radiation, respectively. In the usual sense of exponential absorption (I = Ioe- m x), the attenuation factor is e- m x, where x is the thickness of the material and m is the absorption coefficient. (16 Dec 1997) |
| mass attenuation coefficient | <physics> The mass attenuation coefficient, u/p, of a material for uncharged ionising particles is the quotient of DN/N by pdl, where DN/N is the fraction of particles that experience interactions in traversing a distance dl in a material of density p. (16 Dec 1997) |
| amplification | <molecular biology> An increase in the number of copies of a specific DNA fragment, can be in vivo or in vitro. See: cloning, polymerase chain reaction. (09 Oct 1997) |
| random amplification of polymorphic DNA | <molecular biology> A term originally invented by polymer chemists to describe a disordered tangle of a linear polymer chain with curved sections. In DNA parlance the random coil refers to the structure that results from melting or other forms of separation of the double helix, i.e. Helix coil transition. (18 Nov 1997) |
| gene amplification | <molecular biology> Selective replication of DNA sequence within a cell, producing multiple extra copies of that sequence. The best known example occurs during the maturation of the oocyte of Xenopus, where the set (normally 500 copies) of ribosomal RNA genes is replicated some 4,000 times to give about 2 million copies. (18 Nov 1997) |
| genetic amplification | A process for producing an increase in pertinent genetic material, particularly for increasing the proportion of plasmid DNA to that of bacterial DNA. Includes the production of extrachromosomal copies of the genes for RNA. (05 Mar 2000) |
| DNA amplification | <molecular biology> The use of enzymes in making millions or billions of copies of a single DNA sequence (see PCR). (14 Nov 1997) |
| ligase amplification reaction | <molecular biology> Method for detecting small quantities of a target DNA, with utility similar to PCR. It relies on DNA ligase to join adjacent synthetic oligonucleotides after they have bound the target DNA. Their small size means that they are destabilised by single base mismatches and so form a sensitive test for the presence of mutations in the target sequence. (18 Nov 1997) |