| ameloblastic fibroma | <tumour> A benign mixed odontogenic tumour characterised by neoplastic proliferation of both epithelial and mesenchymal components of the tooth bud without the production of dental hard tissue; presents clinically as a slow-growing painless radiolucency occurring most commonly in the mandible of children and adolescents. (05 Mar 2000) |
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| ameloblastic adenomatoid tumour | A benign epithelial odontogenic tumour appearing radiographically as a well-circumscribed radiolucent-radiopaque lesion usually surrounding the crown of an impacted tooth in an adolescent or young adult; characterised histologically by columnar cells organised in a duct-like configuration interspersed with spindle-shaped cells and amyloid-like deposition that gradually undergoes dystrophic calcification. Synonym: adenoameloblastoma, ameloblastic adenomatoid tumour. (05 Mar 2000) |
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| ameloblastic fibrosarcoma | <tumour> A rapidly growing, painful, destructive, radiolucent odontogenic tumour that usually arises through malignant change in the mesenchymal component of a pre-existing ameloblastic fibroma. Synonym: ameloblastic sarcoma. (05 Mar 2000) |
| ameloblastic layer | The internal layer of the enamel organ. Synonym: enamel layer. (05 Mar 2000) |
| ameloblastic odontoma | <tumour> A benign mixed odontogenic tumour comprised of an undifferentiated component histologically identical to an ameloblastoma and a well differentiated component identical to an odontoma; appears as a mixed radiolucent-radiopaque lesion and presents clinically as an ameloblastoma. Synonym: odontoameloblastoma. (05 Mar 2000) |
| ameloblastic sarcoma | <tumour> A rapidly growing, painful, destructive, radiolucent odontogenic tumour that usually arises through malignant change in the mesenchymal component of a pre-existing ameloblastic fibroma. Synonym: ameloblastic sarcoma. (05 Mar 2000) |
| aponeurotic fibroma | <tumour> A calcifying recurrent non-metastasizing but infiltrating fibroma seen most frequently on the palms of young people as a small firm nodule not attached to the overlying skin. (05 Mar 2000) |
| rabbit fibroma | A connective tissue tumour of cottontail rabbits caused by a poxvirus of the genus Leporipoxvirus and found by Shope to be transmissible with cellular suspensions or Berkefeld filtrates; it is related to myxomatosis and is used in Europe as a source of vaccine to protect against the myxoma virus. Synonym: rabbit fibroma. (05 Mar 2000) |
| rabbit fibroma virus | A poxvirus of the genus Leporipoxvirus, closely related to vaccinia and myxoma viruses, that causes Shope fibroma. Synonym: fibromatosis virus of rabbits, Shope fibroma virus. (05 Mar 2000) |
| giant cell fibroma | <tumour> A tumour of the oral mucosa composed of fibrous connective tissue with large stellate and multinucleate fibroblasts; shares a similar histology with the retrocuspid papilla, fibrous papule of the nose, pearly penile papule, and the ungual fibroma. (05 Mar 2000) |
| central cementifying fibroma | <tumour> A microscopic variant of a central ossifying fibroma. (05 Mar 2000) |
| central ossifying fibroma | <tumour> A painless, slow-growing, expansile, sharply circumscribed benign fibro-osseus tumour of the jaws that is derived from cells of the periodontal ligament; presents initially as a radiolucency that becomes progressively more opaque as it matures. See: central cementifying fibroma. (05 Mar 2000) |
| peripheral ossifying fibroma | A reactive focal gingival overgrowth derived histogenetically from cells of the periodontal ligament and usually developing in response to local irritants (plaque and calculus) on associated teeth; consists microscopically of a hyperplastic cellular fibrous stroma supporting deposits of bone, cementum, or dystrophic calcification. (05 Mar 2000) |
| periungual fibroma | Multiple smooth firm nodules formed at the nail folds, often over 10 mm in length, which appear at or after puberty in some patients with tuberous sclerosis. Synonym: Koenen's tumour. (05 Mar 2000) |
| chondromyxoid fibroma | <radiology> Benign metaphyseal lesion, young adults (60% less than 30 years of age), lytic lesion with well-defined margin, diaphysis of long bone, proximal TIBIA (especially tubercle) most common, NO calcification Differential diagnosis: bubbly bone lesions (12 Dec 1998) |
| concentric fibroma | <tumour> A benign neoplasm, actually a leiomyoma, that occupies the entire circumference of the wall of the uterus. (05 Mar 2000) |