| alpha-keto acid dehydrogenase complex | See: alpha-keto acid dehydrogenase. Anaerobic dehydrogenase, an enzyme (usually a pyridinoenzyme) catalyzing the transfer of hydrogen from some metabolite to some acceptor molecule (e.g., NAD+, cytochrome) other than oxygen; e.g., lactate dehydrogenase's, isocitrate dehydrogenase's, and others in EC class 1, excluding those listed under aerobic dehydrogenase. (05 Mar 2000) |
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| alpha-ketoglutarate dehydrogenase complex | alpha-ketoglutarate dehydrogenase |
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| pyruvate dehydrogenase complex | <enzyme> A complex multienzyme system that catalyses the conversion of (pyruvate + CoA + NAD) to (acetyl CoA + CO2 + NAD). (18 Nov 1997) |
| pyruvate dehydrogenase complex deficiency | An autosomal recessive pyruvate metabolism disorder resulting from deficient enzyme activity in one of several proteins of pyruvate dehydrogenase complex, resulting in deficiency of acetyl CoA. Deficiency in acetyl CoA product reduces the synthesis of acetylcholine, thereby causing neurological abnormalities. Clinical presentations include lactic acidosis, mental retardation, and ataxia. (12 Dec 1998) |
| pyruvate dehydrogenase complex inactivase | <enzyme> Pharmacological action: enzyme inhibitor Registry number: EC 3.4.- (26 Jun 1999) |
| ketoglutarate dehydrogenase complex | <enzyme> Chemical name: 2-Oxoglutarate:lipoamide 2-oxidoreductase (decarboxylating and acceptor-succinylating) Registry number: EC 1.2.4.2 (12 Dec 1998) |
| fatty acid synthase complex | The multienzyme complex that catalyses the formation of palmitate from acetylcoenzyme A, malonylcoenzyme A, and NADPH. (05 Mar 2000) |
| fatty acid synthetase complex | <enzyme> Registry number: EC 6.- (12 Dec 1998) |
| alpha-keto acid dehydrogenase | See: alpha-keto acid dehydrogenase. Anaerobic dehydrogenase, an enzyme (usually a pyridinoenzyme) catalyzing the transfer of hydrogen from some metabolite to some acceptor molecule (e.g., NAD+, cytochrome) other than oxygen; e.g., lactate dehydrogenase's, isocitrate dehydrogenase's, and others in EC class 1, excluding those listed under aerobic dehydrogenase. (05 Mar 2000) |
| malic acid dehydrogenase | <enzyme> An enzyme that catalyses the conversion of (s)-malate and NAD+ to oxaloacetate and NADH. Chemical name: (S)-Malate:NAD+ oxidoreductase Registry number: EC 1.1.1.37 (12 Dec 1998) |
| glycolic acid dehydrogenase | <enzyme> Enzyme from human liver converts glycolate to oxalate, acceptor not identified, not oxygen; free glyoxylate is not an intermediate Registry number: EC 1.1.- (26 Jun 1999) |
| norsolorinic acid dehydrogenase | <enzyme> Catalyses the conversion of norsolorinic acid to averantin Registry number: EC 1.1.1.- (26 Jun 1999) |
| iminodiacetic acid dehydrogenase | <enzyme> Catalyses the conversion of iminodiacetic acid to glycine and glyoxylate; a membrane-bound enzyme isolated from chelatobacter heintzii Registry number: EC 1.5.1.- Synonym: ida-dh, ida dehydrogenase (26 Jun 1999) |
| isocitric acid dehydrogenase | <enzyme> An enzyme of the oxidoreductase class that catalyses the conversion of isocitrate and NAD+ to yield 2-ketoglutarate, carbon dioxide, and NADH. It occurs in cell mitochondria. The enzyme requires magnesium, mn2+; it is activated by ADP, citrate, and calcium, and inhibited by NADH, NADPH, and ATP. The reaction is the key rate-limiting step of the citric acid (tricarboxylic) cycle. (the NADP+ enzyme is EC 1.1.1.42.) Chemical name: Isocitrate:NAD+ oxidoreductase (decarboxylating) Registry number: EC 1.1.1.41 (12 Dec 1998) |
| tropic acid dehydrogenase | <enzyme> Catalyses nad-dependent conversion of tropic acid to phenylacetaldehyde via oxidative decarboxylation; isolated from pseudomonas Registry number: EC 1.1.1.- (26 Jun 1999) |
| 13-hydroxyoctadecadienoic acid dehydrogenase | <enzyme> Nad-dependent enzyme from rat colon mucosa; forms 13-oxooctadecadienoic acid; inhibited by disulfiram Registry number: EC 1.1.1.- Synonym: 13-hode dehydrogenase, 13-roh dehydrogenase (26 Jun 1999) |