| alpha chain disease | A vague or indefinite term; could be used for alpha-heavy-chain disease (a lymphoplasma cell proliferative disease usually seen in Mediterranean men, characterised by intestinal involvement with steatorrhoea, often progressive with fatal outcome) or a thalassaemia (a genetic abnormality in the alpha globin chain of haemoglobin). (05 Mar 2000) |
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| chain, orthodontic chain | <dentistry> A stretchable plastic chain used to hold archwires into brackets and to moke teeth. (08 Jan 1998) |
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| gene rearrangement, alpha-chain T-cell antigen receptor | Ordered rearrangement of T-cell variable gene regions coding for the alpha-chain of antigen receptors. (12 Dec 1998) |
| immunoglobulins, alpha-chain | Heavy chains found in the fab and fc fragments of IgA and having a molecular weight of approximately 58 kD. They contain about 470 amino acid residues arranged in four domains and an oligosaccharide component bound covalently to the fc fragment. (12 Dec 1998) |
| heavy chain disease | A disorder of immunoglobulin synthesis in which large quantities of abnormal heavy chains are excreted in the urine. The amino acid sequences of the n- (amino-) terminal regions of these chains are normal, but they have a deletion extending from part of the variable domain through the first domain of the constant region, so that they cannot form cross-links to the light chains. The defect arises through faulty coupling of the variable (v) and constant (c) region genes. (12 Dec 1998) |
| L-chain disease | bence Jones myeloma |
| alpha, alpha-phosphotrehalase | <enzyme> Forms glucose plus glucose-6-phosphate Registry number: EC 3.2.1.93 Synonym: trehalose-6-phosphate hydrolase, phospho-alpha(1,1)glucosidase, trea gene product, trec gene product (26 Jun 1999) |
| alpha,alpha-trehalose phosphorylase | <enzyme> Chemical name: alpha-d-glucopyranosyl-alpha-d-glucopyranose orthophosphate glucosyltransferase Registry number: EC 2.4.1.64 Synonym: trehalose phosphorylase (26 Jun 1999) |
| alpha-dextrin endo-1,6-alpha-glucosidase | <enzyme> An enzyme with action similar to that of isoamylase; it cleaves 1,6-alpha-glucosidic linkages in pullalan, amylopectin, and glycogen, and in alpha-and beta-amylase limit-dextrins of amylopectin and glycogen. Compare: isoamylase. Synonym: limit dextrinase, pullulanase, R enzyme. (05 Mar 2000) |
| alpha-hydroxymethyl-alpha'-(N-acetylaminomethylene)succinic acid hydrolase | <enzyme> Involved in degradation of vitamin b6; forms acetic acid plus ammonia plus carbon dioxide plus alpha-hydroxymethyl-succinic monoaldehyde Registry number: EC 3.5.1.- Synonym: compound b hydrolase (26 Jun 1999) |
| cholesterol-5 alpha,6 alpha-epoxide hydrase | <enzyme> Aspect of epoxide hydrolase, EC 3.3.2.3 Pharmacological action: carcinogen Registry number: EC 3.3.2.- Synonym: cholesterol epoxide hydrase, cholesterol epoxide hydrolase (26 Jun 1999) |
| CMP-acetylneuraminate-alpha-N-acetylneuramide alpha-2,8-sialyltransferase | <enzyme> Forms ganglioside gd3 Registry number: EC 2.4.99.8 Synonym: cmp-n-acetylneuraminate-gm3 sialyltransferase, gm3-sialosyltransferase, gd3 synthase, gd3-synthase, cmp-n-acetylneuraminate-(n-acetylneuraminyl)-d-galactosyl-d-glucosylceramide sialyltransferase, sialyltransferase II, st II, g(m3) alpha-2,8-sialyltransferase, st8sia I, stii enzyme, stiii enzyme, gt3 synthase (26 Jun 1999) |
| CMP-N-acetylneuraminate-alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase | <enzyme> Enzyme from foetal calf liver; forms branched tetrasaccharide, neuac-alpha2-3gal-beta1-3(neuac-alpha2-6)galnac of fetuin Registry number: EC 2.4.99.3 Synonym: cmp-aag-sialyltransferase, st6galnaci, galnac 2,6-sialyltransferase (26 Jun 1999) |
| NAD 3 alpha-hydroxy-5 alpha-pregnan-20-one-oxidoreductase | <enzyme> From rat liver microsomes Registry number: EC 1.1.1.- Synonym: nad-3-hp-20-oor (26 Jun 1999) |
| 1,4-alpha-d-glucan 6-alpha-d-glucosyltransferase | A glucosyltransferase that transfers an alpha-glucosyl residue in a 1,4-alpha-glucan to the primary hydroxyl group of glucose in a 1,4-alpha-glucan. See: 1,4-alpha-d-glucan branching enzyme. Synonym: oligoglucan-branching glycosyltransferase. (05 Mar 2000) |
| 1,4-alpha-glucan 6-alpha-glucosyltransferase | <enzyme> From aspergillus niger and oryzae Registry number: EC 2.4.1.24 (26 Jun 1999) |