| glucose intolerance | A pathological state in which the fasting plasma glucose level is less than 140 mg per deciliter and the 30-, 60-, or 90-minute plasma glucose concentration following a glucose tolerance test exceeds 200 mg per deciliter. This condition is seen frequently in diabetes mellitus but also occurs with other diseases. (12 Dec 1998) |
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| hereditary fructose intolerance | A metabolic error due to deficiency of hepatic fructose 1,6-bisphosphate aldolase B (which also acts on fructose 1-phosphate); the second enzyme in the specific fructose pathway; vomiting and hypoglycaemia follow ingestion of fructose; prolonged fructose ingestion in young children results in failure to thrive and in jaundice, hepatomegaly, albuminuria, aminoaciduria, and sometimes cachexia and death; autosomal recessive inheritance in most families. (05 Mar 2000) |
| intolerance | Inability to withstand, sensitivity, as to a drug. Origin: L. Tolerare = to bear (18 Nov 1997) |
| lactose intolerance | A disorder characterised by abdominal cramps and diarrhoea after the consumption of food containing lactose (for example milk, ice cream), believed to occur due to a deficiency of intestinal lactase (enzyme that breaks down lactose), may appear first in young adults who have previously tolerated milk well as infants. (27 Sep 1997) |
| fructose intolerance | An autosomal recessive fructose metabolism disorder due to deficient fructose-1-phosphate aldolase (ec 2.1.2.13) activity, resulting in accumulation of fructose-1-phosphate. The accumulated fructose-1-phosphate inhibits glycogenolysis and gluconeogenesis, causing severe hypoglycaemia following ingestion of fructose. Prolonged fructose ingestion in infants leads ultimately to hepatic failure and death. Patients develop a strong distaste for sweet food, and avoid a chronic course of the disease by remaining on a fructose- and sucrose-free diet. (12 Dec 1998) |
| lysinuric protein intolerance | An autosomal recessive disorder characterised by elevated levels of dibasic amino acids (e.g., l-lysine, l-arginine, and l-ornithine) in the urine; apparently due to a defect in dibasic amino acid transport. (05 Mar 2000) |
| alcoholic | 1. Relating to, containing, or produced by alcohol. 2. One who suffers from alcoholism. 3. One who abuses or is dependent upon alcohol. (05 Mar 2000) |
| alcoholic beverages | Drinkable liquids containing ethyl alcohol. (12 Dec 1998) |
| alcoholic cardiomyopathy | <cardiology, pathology> A weakness of the cardiac muscle which is seen in some chronic alcoholics, may be related to a thiamin deficiency or occur for unknown reasons. Origin: Gr. Pathos = disease (27 Sep 1997) |
| alcoholic cirrhosis | <gastroenterology> Alcoholic cirrhosis is a condition of irreversible liver disease due to the chronic inflammatory and toxic effects of ethanol on the liver. In cirrhosis, the liver cells are replaced by fibrous scar tissue. Fibrosis leads to the development of portal hypertension. The development of cirrhosis is directly related to the duration and quantity of alcohol consumption. The manifestations of cirrhosis are related to the liver's inability to not adequately remove waste products from the bloodstream and the effects of portal hypertension. (15 Nov 1997) |
| alcoholic deterioration | Dementia occurring in persons chronically addicted to alcohol. See: chronic alcoholism. (05 Mar 2000) |
| alcoholic encephalopathy | <neurology> Encephalopathy associated with thiamin deficiency. Usually associated with chronic alcohol abuse. Other features include loss of memory and confabulation. Origin: Gr. Pathos = disease (27 Sep 1997) |
| alcoholic extract | A solid extract obtained by extracting the alcohol-soluble principles of a drug, followed by the evaporation of the alcohol. (05 Mar 2000) |
| alcoholic fermentation | The anaerobic formation of ethanol and CO2 from d-glucose. Compare: Gay-Lussac's equation. (05 Mar 2000) |
| alcoholic hyalin | Large, poorly defined accumulations of eosinophilic material in the cytoplasm of damaged hepatic cells in certain forms of cirrhosis and marked fatty change especially due to alcoholism. Synonym: alcoholic hyalin, alcoholic hyaline bodies. (05 Mar 2000) |