| adenosine diphosphate glucose | <chemical> Serves as the glycosyl donor for formation of bacterial glycogen, amylose in green algae, and amylopectin in higher plants. Chemical name: Adenosine 5'-(trihydrogen diphosphate), P'-alpha-D-glucopyranosyl ester (12 Dec 1998) |
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| adenosine 5'-diphosphate | A condensation product of adenosine with pyrophosphoric acid, formed from ATP by the hydrolysis of the terminal phosphate group of the latter compound. Acronym: ADP (05 Mar 2000) |
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| adenosine diphosphate | <biochemistry> ADP is used as an adenine, a ribose and a diphosphate unit. (06 May 1997) |
| adenosine diphosphate ribose | <chemical> Adenosine 5'-(trihydrogen diphosphate),5'-5-ester with d-ribose. An ester formed between the aldehydic carbon of ribose and the terminal phosphate of adenosine diphosphate. Serves as a ribose carrier. Chemical name: Adenosine 5'-(trihydrogen diphosphate), P'-5-ester with D-ribose (12 Dec 1998) |
| adenosine diphosphate ribose cyclase | <enzyme> Catalyses conversion of nadp to 2'-phospho-cyclic adenosine diphosphoribose; do not use for formation of cyclic adpribose (see ADP-ribosyl cyclase) Registry number: EC 4.6.- Synonym: 2'-p-adpr cyclase (26 Jun 1999) |
| adenosine diphosphate sugars | Esters formed between the aldehydic carbon of sugars and the terminal phosphate of adenosine diphosphate. (12 Dec 1998) |
| poly adenosine diphosphate ribose | <chemical> A polynucleotide formed from NAD in the presence of NAD+ nucleosidase. Chemical name: Adenosine 5'-(trihydrogen diphosphate), P'-5-ester with D-ribose, homopolymer (12 Dec 1998) |
| dolichol phosphate glucose-dolichol diphosphate oligosaccharide glucosyltransferase | <enzyme> Can also use dolichol-p-galactose as donor Registry number: EC 2.4.1.- Synonym: dolichol-p-glucose-dolichol-p-p-oligosaccharide glucosyltransferase, dolichol-pp-oligosaccharide glucosyltransferase (ii), dolichol-p-p-oligosaccharide glucosyltransferase (i), dol-p-p-oligosaccharide glycosyltransferase, dppo-glucosyltransferase, dolichyl-p-glucose-man(9)(glcnac)2-pp-dolichol glucosyltransferase (26 Jun 1999) |
| uridine diphosphate glucose | <chemical> A key intermediate in carbohydrate metabolism. Serves as a precursor of glycogen, can be metabolised into udpgalactose and udpglucuronic acid which can then be incorporated into polysaccharides as galactose and glucuronic acid. Also serves as a precursor of sucrose lipopolysaccharides, and glycosphingolipids. Chemical name: Uridine 5'-(trihydrogen diphosphate), P'-alpha-D-glucopyranosyl ester (12 Dec 1998) |
| uridine diphosphate glucose dehydrogenase | <enzyme> An enzyme that catalyses the oxidation of udpglucose to udpglucuronate in the presence of NAD+. Chemical name: UDPglucose:NAD+ 6-oxidoreductase Registry number: EC 1.1.1.22 (12 Dec 1998) |
| adenosine | <biochemistry> A ribonucleotide which consists of the nitrogenous base adenine linked to the sugar ribose. <drug> A cardiac drug used in terminating PSVT involving reentry pathways that include the AV node or Wolff-Parkinson-White syndrome. For atrial flutter, atrial fibrillation, atrial or ventricular tachycardias, adenosine may produce transient AV block that may help identify the rhythm. Pharmacologic action: Endogenous purine nucleoside that depresses AV node and sinus node activity. Brief duration of action (1-2 min). Dose: Rapid 6 mg IV bolus over 1-3 sec. May repeat at 12 mg IV bolus within 1-2 min Patients taking theophylline may require larger doses. Use a smaller dose with cardiac transplant patients. Potential complications: Common but transient - flushing, dyspnea, chest pain, bradycardia, and ventricular ectopy. Theophylline (and caffeine) blocks adenosine's effects. Dipyridamole potentiates adenosine's effects. Use other agents to avoid these drug interactions. (15 Mar 2000) |
| adenosine 3',5'-cyclic monophosphate | An activator of phosphorylase kinase and an effector of other enzymes, formed in muscle from ATP by adenylate cyclase and broken down to 5'-AMP by a phosphodiesterase; sometimes referred to as the "second messenger." A related compound (2',3') is also known. Synonym: cyclic adenylic acid, cyclic AMP, cyclic phosphate. Acronym: cAMP (05 Mar 2000) |
| adenosine 3',5'-cyclic phosphate phosphodiesterase | <enzyme> An enzyme that catalyses the hydrolysis of adenosine 3',5'-cyclic phosphate forming 5'-AMP. A crucial step in the regulation of cellular adenosine 3',5'-cyclic phosphate levels. Inhibited by caffeine. Synonym: cAMP phosphodiesterase. (05 Mar 2000) |
| adenosine 3'-phosphate | 3'-Adenylic acid. See: adenylic acid. (05 Mar 2000) |
| adenosine 3'-phosphate 5'-phosphosulfate | 3'-phosphoadenosine 5'-phosphosulfate;an intermediate in the formation of urinary ethereal sulfates, notable for containing a "high energy" sulfate bond; the 3'-OH of adenosine is replaced by -OPO3H2, the 5'-OH by -OP(O2H)-OSO3H. Synonym: active sulfate. Acronym: PAPS (05 Mar 2000) |
| adenosine-5'-(n-ethylcarboxamide) | <chemical> A stable adenosine a1 and a2 receptor agonist. Experimentally, it inhibits camp and cgmp phosphodiesterase activity. Pharmacological action: antineoplastic agent, vasodilator agents. (12 Dec 1998) |