| acetyl-CoA carboxylase |
[EC 6.4.1.2] a biotin-containing enzyme of the ligase class that catalyzes the carboxylation of acetyl coenzyme A to form malonyl coenzyme A. The reaction is the key rate-controlling step in the synthesis of fatty acids from acetyl groups, and the enzyme requires citrate or isocitrate for activity.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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