| Zenker's fixative | A rapid fixative consisting of mercuric chloride, potassium dichromate, sodium sulfate, glacial acetic acid, and water, useful for trichrome stains; must be washed to remove potassium dichromate and treated with iodine solution to remove mercuric chloride; tissues tend to become brittle if left in the fixative for more than 24 hours. (05 Mar 2000) |
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| formol-Zenker fixative | Zenker's fixative in which glacial acetic acid has been replaced by formalin. (05 Mar 2000) |
| Zenker, Friedrich | <person> German pathologist, 1825-1898. See: Zenker's degeneration, Zenker's diverticulum, Zenker's fixative, Zenker's necrosis, Zenker's paralysis, formol-Zenker fixative. (05 Mar 2000) |
| Zenker's degeneration | A form of severe hyaline degeneration or necrosis in skeletal muscle, occurring in severe infections. Synonym: waxy degeneration, Zenker's necrosis. (05 Mar 2000) |
| Zenker's diverticulum | <pathology> Herniation of the mucosa of the oesophagus through a defect in the wall of the oesophagus. The location is usually in the upper one-third of the oesophagus. (12 Nov 1997) |
| Zenker's necrosis | A form of severe hyaline degeneration or necrosis in skeletal muscle, occurring in severe infections. Synonym: waxy degeneration, Zenker's necrosis. (05 Mar 2000) |
| Zenker's paralysis | Paresthesia and paralysis in the area of the external popliteal nerve. (05 Mar 2000) |
| acetone fixative | Acetone used at low temperatures to fix enzymes, particularly phosphatases; it removes fat and glycogen. (05 Mar 2000) |
| Altmann's fixative | A bichromate-osmic acid fixative. (05 Mar 2000) |
| Bouin's fixative | A solution of glacial acetic acid, formalin, and picric acid, useful for soft and delicate tissues (as those of embryos) and small pieces of tissues; it preserves glycogen and nuclei and permits brilliant staining, but penetrates slowly, distorts kidney tissue and mitochondria, and does not permit Feulgen stain for DNA. (05 Mar 2000) |
| Carnoy's fixative | Ethanol, chloroform, and acetic acid (6:3:1) or ethanol and acetic acid (3:1), an extremely rapid fixative used for glycogen preservation and as a nuclear fixative. (05 Mar 2000) |
| Marchi's fixative | A mixture of Muller's fixative with osmium tetroxide, with potassium chlorate substituted for the potassium dichromate of Muller's fixative for better results; used to demonstrate degenerating myelin. See: Marchi's stain. (05 Mar 2000) |
| Park-Williams fixative | A fixative for spirochetes, comprised of a 2% solution of osmic acid to the fumes of which the bacteria are exposed for a few seconds. (05 Mar 2000) |
| Regaud's fixative | A fixative containing formaldehyde and sodium dichromate, used to preserve mitochondria but not fat; requires afterchroming and extensive washing. (05 Mar 2000) |
| glutaraldehyde fixative | A fixative used in phosphate or cacodylate buffer for electron microscopy, and as a chromatin and enzyme fixative; may be used preceding osmic acid as a second fixative to add membrane preservation for electron microscopy. (05 Mar 2000) |