| x-linked | On the X chromosome. Linked in genetics does not mean merely associated. An x-linked gene travels with the x chromosome and therefore is part of the x chromosome. (12 Dec 1998) |
|---|---|
| X-linked gene | A gene located on an X chromosome. (05 Mar 2000) |
| X-linked hypogammaglobulinaemia | A congenital, X-linked recessive, primary immunodeficiency characterised by decreased numbers (or absence) of circulating B-lymphocytes with corresponding decrease in immunoglobulins of the five classes; associated with marked susceptibility to infection by pyogenic bacteria (notably, pneumococci and Haemophilus influenzae) beginning after loss of maternal antibodies. X-linked hypogammaglobulinaemia with growth hormone deficiency, hypogammaglobulinaemia combined with a reduced number of B-cells; characterised by short stature, delayed puberty, and recurrent infections. (05 Mar 2000) |
| X-linked ichthyosis | A form of ichthyosis, due to 3-beta-hydroxysteroidsulfate sulfatase deficiency, that appears at birth or in early infancy and affects males; characterised by scaling predominantly on the neck and trunk but not on the palms and soles; histologically, there is hyperkeratosis, a granular layer in the epidermis, and normal epidermal cell turnover. Synonym: steroid sulfatase deficiency. (05 Mar 2000) |
| X-linked inheritance | The pattern of inheritance that may result from a mutant gene on an X chromosome. (05 Mar 2000) |
| X-linked locus | Any locus that in normal karyotypes is borne on the X chromosome. (05 Mar 2000) |