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Wright's syndrome <syndrome> Pain running down the arm, numbness, paresthesias, and erythema, with weakness of the hands; due to abduction of the arm for a prolonged period (e.g., during sleep or necessitated by occupation) which stretches the axillary vessels and the nerves of the brachial plexus.
Synonym: subcoracoid-pectoralis minor tendon syndrome, Wright's syndrome.
(05 Mar 2000)
wright One who is engaged in a mechanical or manufacturing business; an artificer; a workman; a manufacturer; a mechanic; especially, a worker in wood; now chiefly used in compounds, as in millwright, wheelwright, etc. "He was a well good wright, a carpenter." (Chaucer)
Origin: OE. Wrighte, writhe, AS. Wyrtha, fr. Wyrcean to work. See Work.
Source: Websters Dictionary
(01 Mar 1998)
Wright, Basil Martin <person> 20th century British physician.
See: Wright respirometer.
(05 Mar 2000)
Wright, James Homer U.S. Pathologist, 1871-1928.
See: Wright's stain.
(05 Mar 2000)
Wright, Marmaduke Burr <person> U.S. Obstetrician, 1803-1879.
See: Wright's version.
(05 Mar 2000)
Wright respirometer An inferential meter to measure tidal and minute volume from the number of revolutions of a vane rotated by the gas stream as the latter passes through 10 tangential slots in a cylindrical stator ring to turn a flat two-bladed rotor.
(05 Mar 2000)
Wright's inbreeding coefficient <genetics> The percentage of homozygous alleles an individual has.
The probability that any two genes in an individual have the same ancestral origin (which is shared by both parents).
(09 Oct 1997)
Wright's stain <technique> A staining mixture of eosinates of polychromed methylene blue used in staining of blood smears.
(05 Mar 2000)
Wright's version A cephalic version employed in cases of shoulder presentation when the shoulders are pushed upward while the breech is moved toward the centre of the uterus by the other hand; the head is then guided into the pelvis.
(05 Mar 2000)
Homer-Wright rosettes Pseudorosettes formed by the arrangement of tumour cells around an area of fibrillarity, evidence of neuroblastic differentiation in a medulloblastoma or primitive neuroectodermal tumour.
(05 Mar 2000)
Aarskog-Scott syndrome A syndrome of ocular hypertelorism, anteverted nostrils, broad upper lip, saddle-bag scrotum, and laxity of ligaments resulting in genu recurvatum, flat feet, and hyperextensible fingers; X-linked and autosomal dominant forms.
Synonym: Aarskog-Scott syndrome.
(05 Mar 2000)
Aarskog syndrome <syndrome> Grier et al. (1983) reported father and 2 sons with typical Aarskog syndrome, including short stature, hypertelorism, and shawl scrotum.
They tabulated the findings in 82 previous cases. X-linked recessive inheritance has been repeatedly suggested. The family reported by Welch (1974) had affected males in 3 consecutive generations. Thus, there is either genetic heterogeneity or this is an autosomal dominant with strong sex-influence and possibly ascertainment bias resulting from use of the shawl scrotum as a main criterion. Stretchable skin was present in the cases of Grier et al. (1983). Teebi et al. (1993) reported the case of an affected mother and 4 sons (including a pair of monozygotic twins) by 2 different husbands. They suggested that the manifestations were as severe in the mother as in the sons and that this suggested autosomal dominant inheritance. Actually, the mother seemed less severely affected, compatible with X-linked inheritance.
Clinical signs: Mild to moderate short stature,normocephaly, Widow's peak hair, maxillary hypoplasia, broad nasal bridge, anteverted nostrils, long philtrum, broad upper lip, curved linear dimple below the lower lip, hypertelorism, ptosis, down-slanted palpebral fissures, ophthalmoplegia, strabismus, hyperopic astigmatism, large cornea, floppy ears, lop-ears,cleft lip/palate, shawl scrotum, saddle-bag scrotum, cryptorchidism, brachydactyly, digital contractures, clinodactyly, mild syndactyly, transverse palmar crease, lymphoedema of the feet, ligamentous laxity, osteochondritis dissecans, proximal finger joint hyperextensibility, flexed distal finger joints, genu recurvatum, flat feet, stretchable skin, cervical spine hypermobility, odontoid anomaly, macrocytic anaemia, hemochromatosis, hepatomegaly, portal cirrhosis, imperforate anus, rectoperineal fistula, interstitial pulmonary disease, sternal deformity.
Inheritance: Sex-influenced autosomal dominant form, also X-linked form.
(05 Aug 1998)
abdominal muscle deficiency syndrome <syndrome> Congenital absence (partial or complete) of abdominal muscles, in which the outline of the intestines is visible through the protruding abdominal wall; in males, genitourinary anomalies (urinary tract dilation and cryptorchidism) are also found; genetics unclear.
(05 Mar 2000)
abstinence syndrome <syndrome> A constellation of physiologic changes undergone by persons or animals who have become physically dependent on a drug or chemical due to prolonged use at elevated doses, but who are abruptly deprived of that substance. The abstinence syndrome varies with the drug to which dependence has developed. Generally the effects observed are in an opposite direction from those produced by the drug; e.g., the withdrawal syndrome from central nervous system depressants such as barbiturates and benzodiazepines consists of insomnia, restlessness, tremulousness, hallucinations, and, in the extreme, tonic-clonic convulsions which may prove fatal. The onset time and severity of the abstinence syndrome depend upon how rapidly the drug disappears from the body.
(05 Mar 2000)
Achard syndrome <syndrome> Arachnodactyly with small receding mandible, broad skull, and joint laxity limited to the hands and feet; genetics unclear.
(05 Mar 2000)
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