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wegener granulomatosis <radiology> Sinuses, mucoperiosteal thickening, may destroy bone and cartilage, lungs, necrotizing granulomata, multiple round nodules (2 mm - 9 cm), may cavitate, kidneys, glomerulonephritis most likely to be necrosis of capillary tuft, generalised necrotizing vasculitis of arteries and veins, auto-immune: basement membrane, almost always involves lungs, M = F, 30-50 years of age, symptoms: cough, haemoptysis, fever, wt loss, multiple respecially infections, treatment: cytotoxins, immunosuppression
(12 Dec 1998)
Wegener's granulomatosis <immunology, nephrology> Wegener's granulomatosis or midline granulomatosis is a rare disorder characterised by chronic tissue inflammation (due to the inflammation of blood vessels) and granuloma (aggregates of cells) formation in the nasal passages, lungs and kidneys.
(27 Sep 1997)
Wegener, Friedrich <person> German pathologist, 1907-1990.
See: Wegener's granulomatosis.
(05 Mar 2000)
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