| vinca alkaloid | <drug, oncology> Anti-cancer drugs originally derived from the common periwinkle Catharantus roseus. Drugs of this type include vincristine, vinblastine. (14 Oct 1997) |
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| vinca alkaloids | <chemical> A class of alkaloids from the genus of apocyanaceous woody herbs including periwinkles. They are some of the most useful antineoplastic agent. Pharmacological action: antineoplastic agent, phytogenic, vasodilator agents. (12 Dec 1998) |
| Vinca rosea | A species of myrtle (family Myrtaceae) used in various parts of the world as a home remedy; two active dimeric alkaloids obtained from this plant are vinblastine and vincristine. Synonym: periwinkle. (05 Mar 2000) |
| vincaleucoblastine | A dimeric alkaloid obtained from Vinca rosea. It arrests mitosis in metaphase (although vincristine is more active in this respect) and exhibits greater antimetabolic activity than does vincristine; used in the treatment of Hodgkin's disease, choriocarcinoma, acute and chronic leukaemias, and other neoplastic diseases; blocks microtubule assembly. Synonym: vincaleucoblastine. (05 Mar 2000) |
| vincamine | <chemical> A major alkaloid of vinca minor l., apocynaceae. It has been used therapeutically as a vasodilator and antihypertensive agent, particularly in cerebrovascular disorders. Pharmacological action: antihypertensive agents, vasodilator agents. Chemical name: Eburnamenine-14-carboxylic acid, 14,15-dihydro-14-hydroxy-, methyl ester, (3alpha,14beta,16alpha)- (12 Dec 1998) |