| vidarabine |
In the 1950s two nucleosides were isolated from the Caribbean sponge Tethya crypta: spongothymidine and spongouridine; which contained an arabinoside sugar rather than a ribose. These compounds led to the synthesis of a new generation, sugar modified nucleoside analog: vidarabine, and the related compound: cytarabine. In 2004 these were the only marine related compounds in clinical use [1].The anti-viral activity of vidarabine was first described by M. Privat de Garilhe and J. ...
Ãâó: en.wikipedia.org/wiki/Vidarabine
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