| non-insulin-dependent diabetes mellitus | <disease> An often mild form of diabetes mellitus of gradual onset, usually in obese individuals over age 35; absolute plasma insulin levels are normal to high, but relatively low in relation to plasma glucose levels; ketoacidosis is rare, but hyperosmolar coma can occur; responds well to dietary regulation and/or oral hypoglycaemic agents, but diabetic complications and degenerative changes can develop. (05 Mar 2000) |
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| diabetes mellitus | <disease> Relative or absolute lack of insulin leading to uncontrolled carbohydrate metabolism. In juvenile onset diabetes (that may be an autoimmune response to pancreatic _ cells) the insulin deficiency tends to be almost total, whereas in adult onset diabetes there seems to be no immunological component but an association with obesity. (18 Nov 1997) |
| diabetes mellitus, experimental | Diabetes mellitus induced experimentally by administration of various diabetogenic agents or by pancreatectomy. (12 Dec 1998) |
| diabetes mellitus, insulin-dependent | Diabetes mellitus characterised by insulin deficiency, sudden onset, severe hyperglycaemia, rapid progression to ketoacidosis, and death unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence. (12 Dec 1998) |
| diabetes mellitus, lipoatrophic | A disorder characterised by complete absence of subcutaneous adipose tissue, insulin-resistant diabetes with little tendency to ketoacidosis, hyperlipidemia with subcutaneous xanthomatosis, hepatomegaly, and an elevated basal metabolic rate. (12 Dec 1998) |
| diabetes mellitus, non-insulin-dependent | Diabetes characterised by the ability to survive without ketoacidosis in the absence of insulin therapy. It is usually of slow onset and patients exhibit a tendency to obesity. (12 Dec 1998) |
| insulin-dependent diabetes mellitus | A chronic condition in which the pancreas makes little or no insulin because the beta cells have been destroyed. The body is then not able to use the glucose (blood sugar) for energy. IDDM usually comes on abruptly, although the damage to the beta cells may begin much earlier. The signs of IDDM are a great thirst, hunger, a need to urinate often, and loss of weight. To treat the disease, the person must inject insulin, follow a diet plan, exercise daily, and test blood glucose several times a day. IDDM usually occurs in children and adults who are under age 30. This type of diabetes used to be known as juvenile diabetes, juvenile-onset diabetes, and ketosis-prone diabetes. (09 Oct 1997) |
| type I diabetes mellitus | <endocrinology> A severe metabolic disorder which has an abrupt onset before the age of twenty. In it, an insulin deficiency prevents the body from using carbohydrates properly and forces it to rely mainly on protein metabolism. Treatment of the disease includes strict dietary regulation and mandatory insulin injections. (09 Oct 1997) |
| adult-onset diabetes | <disease> An often mild form of diabetes mellitus of gradual onset, usually in obese individuals over age 35; absolute plasma insulin levels are normal to high, but relatively low in relation to plasma glucose levels; ketoacidosis is rare, but hyperosmolar coma can occur; responds well to dietary regulation and/or oral hypoglycaemic agents, but diabetic complications and degenerative changes can develop. (05 Mar 2000) |
| alimentary diabetes | Glycosuria developing after the ingestion of a moderate amount of sugar or starch, which normally is disposed of without appearing in the urine, because rate of intestinal absorption exceeds capacity of the liver and the other tissues to remove the glucose, thus allowing blood glucose levels to become high enough for renal excretion to occur. Synonym: alimentary diabetes, digestive glycosuria. (05 Mar 2000) |
| alloxan diabetes | Experimental diabetes mellitus produced in animals by the administration of alloxan, which damages the insulin-producing islet cells of the pancreas. (05 Mar 2000) |
| brittle diabetes | <endocrinology> A term used when the blood glucose (sugar) level often swings quickly from high to low and from low to high and is somewhat unstable. (13 Nov 1997) |
| bronzed diabetes | A genetic disease in which the body takes in too much iron from food, this causes excess iron to be deposited in the liver and heart and other organs, eventually leading to organ failure and death. This illness is called bronze diabetes because the kidneys often fail, leading to symptoms similar to those found with diabetes mellitus, and because the deposition of iron into the skin makes the person look like he or she has an all-over tan. It used to be believed that this disease was rare and mainly affected people of Caucasian descent, butin recent years scientists have realised it is more common and affects a wide range of ethnic groups. Some believe that this genetic defect actually helps people (especially women) survive in areas where malnutrition is widespread and iron is scarce in food. Regular venesection may help people suffering from this disease. (09 Oct 1997) |
| bronze diabetes | A genetic disease in which the body takes in too much iron from food, this causes excess iron to be deposited in the liver and heart and other organs, eventually leading to organ failure and death. This illness is called bronze diabetes because the kidneys often fail, leading to symptoms similar to those found with diabetes mellitus, and because the deposition of iron into the skin makes the person look like he or she has an all-over tan. It used to be believed that this disease was rare and mainly affected people of Caucasian descent, butin recent years scientists have realised it is more common and affects a wide range of ethnic groups. Some believe that this genetic defect actually helps people (especially women) survive in areas where malnutrition is widespread and iron is scarce in food. Regular venesection may help people suffering from this disease. (09 Oct 1997) |
| calcinuric diabetes | <biochemistry> The excretion of abnormally large amounts of calcium in the urine, seen in cases of hyperparathyroidism. Origin: Gr. Ouron = urine (11 Jan 1998) |