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UDPglucose a nucleotide derivative of glucose; it donates glucosyl groups in the synthesis of glycogen and other polysaccharides. It is the parent compound from which the other UDPhexoses are synthesized.
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UDPglucose 4-epimerase [EC 5.1.3.2] an enzyme of the isomerase class that catalyzes the interconversion of UDPgalactose and UDPglucose in the metabolism of galactose, requiring NAD+ as a cofactor. Deficiency of the enzyme in erythrocytes, an autosomal recessive trait, causes accumulation in red cells of galactose 1-phosphate. Called also UDPgalactose 4-epimerase.
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UDPglucose 6-dehydrogenase [EC 1.1.1.22] an enzyme of the oxidoreductase class that catalyzes the oxidation of UDPglucose to UDPglucuronate, using NAD+ as an electron acceptor.
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UDPglucose pyrophosphorylase UTP–glucose-1-phosphate uridylyltransferase.
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UDPglucose–hexose-1-phosphate uridylyltransferase [EC 2.7.7.12] an enzyme of the transferase class that catalyzes the exchange of galactose 1-phosphate for the glucose 1-phosphate moiety of UDPglucose, forming UDPgalactose and glucose 1-phosphate. The reaction is the second step in the utilization of galactose as a fuel. Lack of enzyme activity, an autosomal recessive trait, causes galactosemia. Called also galactose 1-phosphate uridyltransferase, hexose 1-phosphate uridylyltransferase, and uridyl transferase.
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