| BRCA1 breast cancer susceptibility gene | This mutated (changed) version of the BRCA1 gene makes a person susceptible to developing breast cancer. (12 Dec 1998) |
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| breast cancer susceptibility genes | Inherited factors that predispose to breast cancer. Put otherwise, these genes make one more susceptible to the disease and so increase the risk of developing breast cancer. Two of these genes, BRCA1 and BRCA2, have been identified (and prominently publicised). Several other genes (those for the Li-Fraumeni syndrome, Cowden disease, Muir-Torre syndrome, and ataxia-telangiectasia) are also known to predispose to breast cancer. However, since all of these known breast cancer susceptibility genes together do not account for more than a minor fraction (1/5th at most) of breast cancer that clusters in families, it is clear that more breast cancer genes remain to be discovered. (12 Dec 1998) |
| cancer, breast, susceptibility genes | Inherited factors that predispose to breast cancer. Put otherwise, these genes make one more susceptible to the disease and so increase the risk of developing breast cancer. Two of these genes, BRCA1 and BRCA2, have been identified (and prominently publicised). Several other genes (those for the Li-Fraumeni syndrome, Cowden disease, Muir-Torre syndrome, and ataxia-telangiectasia) are also known to predispose to breast cancer. However, since all of these known breast cancer susceptibility genes together do not account for more than a minor fraction (1/5th at most) of breast cancer that clusters in families, it is clear that more breast cancer genes remain to be discovered. (12 Dec 1998) |
| cancer susceptibility gene | tumour suppressor gene |
| genes, breast cancer susceptibility | Inherited factors that predispose to breast cancer. Put otherwise, these genes make one more susceptible to the disease and so increase the risk of developing breast cancer. Two of these genes, BRCA1 and BRCA2, have been identified (and prominently publicised). Several other genes (those for the Li-Fraumeni syndrome, Cowden disease, Muir-Torre syndrome, and ataxia-telangiectasia) are also known to predispose to breast cancer. Howeverm, since all of these known breast cancer susceptibility genes together do not account for more than a minor fraction (1/5th at most) of breast cancer that clusters in families, it is clear that more breast cancer genes remain to be discovered. See related entries to: BRCA1; BRCA2; Breast cancer, familial. (12 Dec 1998) |
| colourimetric caries susceptibility test | A colourimetric test for determining dental caries activity or susceptibility based on the rate of acid production by acidogenic oral microorganisms (e.g., lactobacillus) in a glucose medium, using bromcresol green as the indicator, and producing a colour change from green to yellow. Synonym: colourimetric caries susceptibility test. (05 Mar 2000) |
| susceptibility | Origin: Cf. F. Susceptibilite. 1. The state or quality of being susceptible; the capability of receiving impressions, or of being affected. 2. Specifically, capacity for deep feeling or emotional excitement; sensibility, in its broadest acceptation; impressibility; sensitiveness. <physics> Magnetic susceptibility, the intensity of magnetization of a body placed in a uniform megnetic field of unit strength. Synonym: Capability, sensibility, feeling, emotion. Source: Websters Dictionary (01 Mar 1998) |
| susceptibility testing | The determination of the ability of an antibiotic to kill or inhibit the growth of bacteria. (05 Mar 2000) |
| disease susceptibility | A constitution or condition of the body which makes the tissues react in special ways to certain extrinsic stimuli and thus tends to make the individual more than usually susceptible to certain diseases. (12 Dec 1998) |
| acute miliary tuberculosis | A rapidly fatal disease due to the general dissemination of tubercle bacilli in the blood, resulting in the formation of miliary tubercles in various organs and tissues, and producing symptoms of profound toxaemia. Synonym: acute miliary tuberculosis, disseminated tuberculosis. (05 Mar 2000) |
| acute tuberculosis | A rapidly fatal disease due to the general dissemination of tubercle bacilli in the blood, resulting in the formation of miliary tubercles in various organs and tissues, and producing symptoms of profound toxaemia. Synonym: acute miliary tuberculosis, disseminated tuberculosis. (05 Mar 2000) |
| adult tuberculosis | Tuberculosis found in adults and characterised by lesions near the apex of an upper lobe, which may cavitate or heal with scarring without spreading to lymph nodes; theoretically, secondary tuberculosis may be due to exogenous reinfection or to reactivation of a dormant endogenous infection. Synonym: adult tuberculosis, postprimary tuberculosis, reinfection tuberculosis. (05 Mar 2000) |
| aerogenic tuberculosis | Infection with the Mycobacterium tuberculosis spread by inhalation of infected droplets. (05 Mar 2000) |
| anthracotic tuberculosis | <chest medicine> Fibrosis and scarring of the lungs secondary to the repeated inhalation of dust associated with some occupation. Examples include silica, asbestos and coal dust exposure. (29 Oct 1998) |
| arrested tuberculosis | A scar or a calcified, fibrous, or caseous nodule in the lung pleura, lymph node, or other organ, resulting from previous tuberculosis that has regressed; reactivation is possible. Synonym: arrested tuberculosis, inactive tuberculosis. (05 Mar 2000) |