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trimethoprim <drug> A drug that inhibits the reduction of dihydrofolate to tetrahydrofolate (a later step than that inhibited by sulphonamides).
Selective for some bacterial dihydrofolate reductases and often used in conjunction with sulphonamides.
(19 Jan 1998)
trimethoprim resistance Nonsusceptibility of a bacterium to the action of trimethoprim.
(12 Dec 1998)
trimethoprim-sulfamethoxazole A drug combination consisting of a dihydrofolate reductase inhibitor (trimethoprim) and a sulfonamide antibacterial drug (sulfamethoxazole). The drug combination is synergistic as the drugs interfere with two successive steps in the formation/utilization of folic acid by microorganisms. Used to treat many infectious diseases.
(05 Mar 2000)
trimethoprim-sulfamethoxazole combination <chemical> 4-amino-n-(5-methyl-3-isoxazolyl)benzenesulfonamide mixture with 5-((3,4,5-trimethoxyphenyl)methyl)- 2,4-pyrimidinediamine. This drug combination has proved to be an effective therapeutic agent with broad-spectrum antibacterial activity against both gram-positive and gram-negative organisms. It is effective in the treatment of many infections, including pneumocystis carinii pneumonia in aids, but is the drug of choice for urinary infection.
Pharmacological action: anti-infective agents, anti-infective agents, urinary, antimalarials.
Chemical name: Benzenesulfonamide, 4-amino-N-(5-methyl-3-isoxazolyl)-, mixt. With 5-((3,4,5-trimethoxyphenyl)methyl)-2,4-pyrimidinediamine
(12 Dec 1998)
administration, oral The giving of drugs, chemicals, or other substances by mouth.
(12 Dec 1998)
cancer, oral Cancer of the mouth area. A sore in the mouth that does not heal can be a warning sign of oral cancer. A biopsy is the only to know whether as abnormal area in the oral cavity is cancer. Oral cancer is caused by tobacco (smoking and chewing) and alcohol use. Surgery to remove the tumour in the mouth is the usual treatment for patients with oral cancer.
(12 Dec 1998)
candidiasis, oral Infection of the mucous membranes of the mouth by a fungus of the genus candida.
(12 Dec 1998)
canine oral papilloma Warts affecting mucous membranes of young dogs; caused by a papillomavirus.
(05 Mar 2000)
magnesia and alumina oral suspension A mixture of magnesium hydroxide and variable amounts of aluminum oxide; used as an antacid.
(05 Mar 2000)
pathology, oral A dental specialty concerned with pathology of the oral cavity.
(12 Dec 1998)
pharyngo-oral Relating to the pharynx and the mouth; oropharyngeal.
Origin: pharyngo-+ L. Os (or-), mouth
(05 Mar 2000)
combination oral contraceptive A mixture of a steroid having progestational activity and an oestrogen.
(05 Mar 2000)
contraceptives, oral Compounds, usually hormonal, taken orally in order to block ovulation and prevent the occurrence of pregnancy. The hormones are generally oestrogen or progesterone or both.
(12 Dec 1998)
contraceptives, oral, combined Fixed drug combinations administered orally for contraceptive purposes.
(12 Dec 1998)
contraceptives, oral, hormonal Oral contraceptives which owe their effectiveness to hormonal preparations.
(12 Dec 1998)
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