| bacterial transposition | <molecular biology> A short sequence of DNA (known as a transposon) which can change location on the bacterial genome (the sum total of all of the bacterium's DNA) and contains genes which code for proteins that enable it to change location. They are useful because they can also contain genes for other things, like antibiotic resistance, and because they can be introduced into a bacterial genome by a researcher. (09 Oct 1997) |
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| penoscrotal transposition | Deficient ventral penile shaft skin which is buried in scrotum or tethered to scrotal midline by a fold or web of skin. The urethra and erectile bodies are usually normal. Synonym: penis palmatus, penoscrotal transposition. (05 Mar 2000) |
| corrected transposition of the great vessels | Anatomically or physiologically corrected malposition of the great arteries. In anatomically corrected transposition, they arise from the correct ventricles but have an abnormal relation to each other (actually a malposition rather than a transposition.) In physiologically or functionally corrected transposition, the aorta arises from a systemic ventricle that has the morphologic characteristics of a right ventricle, and the pulmonary artery arises from a "venous" ventricle that has the morphologic characteristics of a left ventricle. (05 Mar 2000) |
| transposition | <molecular biology> The movement of a piece of DNA around the chromosome (from one gene to another part of the genome), usually through the function of a transposable element. (09 Oct 1997) |
| transposition of arterial stems | Congenital malformation in which the aorta arises from the morphologic right ventricle and the pulmonary artery from the morphologic left ventricle resulting in two separate and parallel circulations. The condition is lethal unless some communication exists between the systemic and pulmonic circulation after birth; otherwise, unoxygenated venous blood inappropriately enters the systemic circulation, and oxygenated pulmonary venous blood is inappropriately directed to the pulmonary circulation. The life sustaining communication may be an intra-atrial passage or a patent ductus arteriosus. Synonym: transposition of arterial stems. (05 Mar 2000) |
| transposition of great vessels | <embryology> A congenital cardiovascular malformation in which the aorta arises entirely from the right ventricle and the pulmonary artery from the left ventricle, so that the venous return from the peripheral circulation is recirculated by the right ventricle via the aorta to the systemic circulation without being oxygenated in the lungs. There is an intracardiac shunt, increased pulmonary vascularity, cyanosis. The chest X-ray shows that the heart size may be normal at birth, but it gradually enlarges with a globular or egg-on-its-side appearance. (27 Jun 1999) |
| transposition of the great vessels | Congenital malformation in which the aorta arises from the morphologic right ventricle and the pulmonary artery from the morphologic left ventricle resulting in two separate and parallel circulations. The condition is lethal unless some communication exists between the systemic and pulmonic circulation after birth; otherwise, unoxygenated venous blood inappropriately enters the systemic circulation, and oxygenated pulmonary venous blood is inappropriately directed to the pulmonary circulation. The life sustaining communication may be an intra-atrial passage or a patent ductus arteriosus. Synonym: transposition of arterial stems. (05 Mar 2000) |
| truncus vs. Transposition | <radiology> May look very similar, increased PBF and cyanosis (admixture), distinguishing feature: aortic arch, right aortic arch in 30% of TA vs. Only 5% of TGV (12 Dec 1998) |
| behavioural genetics | The study of heritable factors in behavioural patterns, as by pedigree analysis, biochemical abnormality, or karyotypic analysis. (05 Mar 2000) |
| biochemical genetics | The study of genetics in terms of the chemical (biochemical) events involved, as in the manner in which DNA molecules replicate and control the synthesis of specific enzymes by the genetic code. (05 Mar 2000) |
| biometrical genetics | <study> The mathematical approach to the study of the inheritance of different phenotypes, or physical characteristics, as a result of plant or animal breeding. (09 Oct 1997) |
| Galtonian-Fisher genetics | The genetics of measurable traits determined by multiple loci which make contributions that are independent, additive, and approximately equal. Synonym: multilocal genetics. (05 Mar 2000) |
| galtonian genetics | The study of traits by analysis of the first two moments of metrical data; the preferred method for analysis of traits following the multivariate gaussian distribution. (05 Mar 2000) |
| palindrome in genetics | A palindrome is a word that reads the same in both directions as, for example, the names eve or anna. In genetics, a palindrome is a DNA or RNA sequence that reads the same in both directions. The sites of many restriction enzymes that cut (restrict) DNA are palindromes. Palindromic rheumatism is a form of joint inflammation whereby the joints involved appears to change periodically from one region of the body to another and back again. (12 Dec 1998) |
| variation (genetics) | The phenotypic differences among individuals in a population. (12 Dec 1998) |