| transmembrane protein | <cell biology> A protein subunit in which the polypeptide chain is exposed on both sides of the membrane. The term does not apply when different subunits of protein complex are exposed at opposite surfaces. most integral membrane proteins are also transmembrane proteins. (13 Nov 1997) |
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| catabolite gene activator protein | <molecular biology, protein> A regulatory protein that triggers the transcription of genes that generate the enzymes bacteria need to usenutrients when glucose isabsent. (16 Mar 1998) |
| catabolite (gene) activator protein | A protein that can be activated by cAMP, whereupon it affects the action of RNA polymerase by binding it with it or near it on the DNA to be transcribed. Synonym: cAMP receptor protein, catabolite gene activator. (05 Mar 2000) |
| protein activator, aminolevulinic acid synthetase | <chemical> From rat liver mitochondria Synonym: aminolevulinic acid synthetase activator (26 Jun 1999) |
| cystic fibrosis transmembrane conductance regulator | Gene believed to be defective in cystic fibrosis. Gene encodes a chloride channel, homologous to a family of proteins that actively transport small solutes in an ATP dependent manner (ABC transporters). The regulator protein is a protein which is embedded in the cell membrane and acts as a channel for certain ions to be transported into or out of the cell. The disease cystic fibrosis is caused by a defect in the gene for this protein. (09 Oct 1997) |
| hepatoma transmembrane kinase | <enzyme> A transmembrane tyrosine kinase of the eph subfamily; genbank u07695 Registry number: EC 2.7.1.- Synonym: htk protein, htk gene product (26 Jun 1999) |
| transmembrane | Through or across a membrane. (05 Mar 2000) |
| transmembrane potential | <physiology> More correctly, transmembrane potential difference: the electrical potential difference across a plasma membrane. See: resting potential, action potential. (18 Nov 1997) |
| transmembrane transducer | A system that transmits a chemical or electrical signal across a membrane. Usually involves a transmembrane receptor protein that is thought to undergo a conformation change that is expressed on the inner surface of the membrane. Many such transducing species are dimeric and the conformation change may involve interaction between the two components. (18 Nov 1997) |
| activator | <biochemistry> A DNA-binding transcription metabolite that positively modulates an allosteric enzyme or regulates one or more genes by increasing the rate of transcription. (12 Mar 1998) |
| activator appliances | Loose-fitting removable orthodontic appliances which redirect the pressures of the facial and masticatory muscles onto the teeth and their supporting structures to produce improvements in tooth arrangements and occlusal relations. (12 Dec 1998) |
| catabolite gene activator | catabolite (gene) activator protein |
| plasminogen activator | <enzyme> Serine protease that acts on plasminogen to generate plasmin. Has also been implicated in invasiveness and is produced by many normal and invasive cells. The vascular form (tPA, 55 kD) is very similar to tissue plasminogen activator (uPA, 70 kD) and to streptokinase and urokinase. (18 Nov 1997) |
| plasminogen activator inhibitor 1 | <chemical> A member of the serpin family of proteins. It inhibits both the tissue-type and urokinase-type plasminogen activator. Pharmacological action: serine proteinase inhibitors. (12 Dec 1998) |
| plasminogen activator inhibitor 2 | <chemical> Member of the serpin family of proteins. It inhibits both the tissue-type and urokinase-type plasminogen activator. Pharmacological action: serine proteinase inhibitors. (12 Dec 1998) |