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topotecan <drug, oncology> This alkaloid chemotherapy drug is a derivative of the drug camptothecin, which was originally isolated from a Chinese tree, Camptotheca acuminata but has also been found in the nothapodytes tree (Nothapodytes foetida).Topotecan is a DNA topoisomerase I inhibitor and is used to treat advanced ovarian cancer.
(09 Oct 1997)
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