| topotecan hydrochloride |
a cytotoxic inhibitor of DNA topoismerase (type I topoisomerase), which prevents the rejoining of DNA strands following breakage by DNA topoisomerase, leading to double-strand DNA breakage and cell death, used as a secondary agent in the treatment of metastatic ovarian carcinoma and refractory small cell lung carcinoma; administered by intravenous infusion.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
|
|---|