| tetracycline | <drug> Broad spectrum antibiotic that blocks binding of aminoacyl tRNA to the ribosomes of both gram-positive and gram-negative organisms (and those of organelles). Produced by Streptomyces aureofasciens. Other exaples include tetracycline, demeclocycline and doxycycline. (09 Oct 1997) |
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| tetracycline 5a(11a)dehydrogenase | <enzyme> Catalyses the oxidation of 7-chloro-5a(11a)-dehydrotetracycline to 7-chlorotetracycline; uses nadp Registry number: EC 1.3.1.- (26 Jun 1999) |
| tetracycline resistance | Nonsusceptibility of a microbe (usually a bacterium) to the action of tetracycline, which binds to the 30s ribosomal subunit and prevents the normal binding of aminoacyl-trna. (12 Dec 1998) |
| tetracyclines | Closely congeneric derivatives of the polycyclic naphthacenecarboxamide. (gilman et al., goodman and gilman's the pharmacological basis of therapeutics, 8th ed, p1117) (12 Dec 1998) |
| antibiotics, tetracycline | <chemical> Broad-spectrum natural and semisynthetic antibiotics with a naphthacene structure obtained from various streptomyces species. Pharmacological action: protein synthesis inhibitor. (12 Dec 1998) |
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