| Tay-Sachs carrier | <genetics> One who carries the recessive gene that is responsible for Tay-Sachs disease. Genetic testing for this fatal disease is crucial so that Tay-Sachs carriers can be identified and provided with genetic counseling. (27 Sep 1997) |
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| Tay-Sachs disease | <disease> A genetic disorder found in east European Jewish families which can result in early death bu affecting the brain and nerves by causing abnormal lipid metabolism. It is a lysosomal disease in which there is a deficiency of hexosaminidase A, an enzyme that degrades ganglioside GM2. Symptoms appear at age 3-6 months and include blindness, deafness, seizures, paralysis, dementia, decreased muscle tone and growth retardation. There is no known treatment and most children usually die between 2 and 5 years of age. Inheritance: autosomal recessive. (06 Oct 1997) |
| Tay's cherry-red spot | The ophthalmoscopic appearance of the normal choroid beneath the fovea centralis, appearing as a red spot surrounded by white retinal oedema in central artery closure or lipid infiltration in sphingolipidosis. Synonym: Tay's cherry-red spot. (05 Mar 2000) |
| Tay, Warren | <person> English physician, 1843-1927. See: Tay's cherry-red spot, Tay-Sachs disease. (05 Mar 2000) |
| anterior choroiditis | Disseminated choroiditis restricted to peripheral choroid. (05 Mar 2000) |
| areolar choroiditis | Inflammation of the choroid, with prominent pigment proliferation occurring first in the macular region and then more peripherally. (05 Mar 2000) |
| metastatic choroiditis | Inflammation of the choroid arising from microbial emboli. (05 Mar 2000) |
| choroiditis | <pathology> Inflammation of the choroid, a membrane or coat of the eyeball. (27 Sep 1997) |
| multifocal choroiditis | Macular, peripapillary, and peripheral choroiditis, often designated presumed ocular histoplasmosis. (05 Mar 2000) |
| posterior choroiditis | Disseminated choroiditis restricted to the central choroid. (05 Mar 2000) |
| proliferative choroiditis | The dense scar tissue produced by severe choroiditis. (05 Mar 2000) |
| suppurative choroiditis | Purulent inflammation of the choroid. (05 Mar 2000) |
| diffuse choroiditis | A widespread exudative inflammation of the choroid, with progressive resolution of older lesions as new ones occur. (05 Mar 2000) |
| disseminated choroiditis | Chronic inflammation of the choroid, with multiple isolated foci. (05 Mar 2000) |
| juxtapupillary choroiditis | Choroiditis adjacent to the optic disk. (05 Mar 2000) |