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Tn <abbreviation> Ocular tension.
(05 Mar 2000)
TNF <cytokine> Originally described as a tumour inhibiting factor in the blood of animals exposed to bacterial lipopolysaccharide or Bacille Calmette-Guerin.
Preferentially kills tumour cells in vivo and in vitro, causes necrosis of certain transplanted tumours in mice and inhibits experimental metastases. Human Tumour Necrosis factor alpha is a protein of 157 amino acids and has a wide range of pro inflammatory actions. Usually considered a cytokine.
Synonym: cachectin.
Acronym: TNF
(13 Nov 1997)
TNF-IL1-activated protein kinase <enzyme> Phosphorylates beta casein in vitro; not the same as casein kinase 1 and casein kinase 2; not activated by mitogens, celllular stresses or any other cytokines than il1 and tnf
Registry number: EC 2.7.1.-
Synonym: tip kinase, beta casein kinase
(26 Jun 1999)
TNM <abbreviation> Tumour-node-metastasis.
See: TNM staging.
(05 Mar 2000)
TNM classification TNM classification provides a system for staging the occurrence of cancer., T refers to the primary tumour and is categorised as being 1-4 and a-d depending upon site, size and spread, N refers to the lymph nodes and they are categorised as being X,0, 1, 2, or 3 depending upon if any, some or all are involved metastasis, and M to the presence or absence of distant metasteses. Refer Staging.
(16 Dec 1997)
TNM staging A system of clinicopathologic evaluation of tumours based on the extent of tumour involvement at the primary site (T, followed by a number indicating size and depth of invasion), and lymph node involvement (N) and metastasis (M) each followed by a number starting at 0 for no evident metastasis; numbers used depend on the organ involved and influence the prognosis and choice of treatment.
(05 Mar 2000)
tnpI recombinase <enzyme> From tn2i and related beta-lactamase transposons
Registry number: EC 2.7.7.-
(26 Jun 1999)
TNT <abbreviation> Trinitrotoluene.
(05 Mar 2000)
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