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Acquired Immunodeficiency Syndrome <immunology, syndrome> An epidemic disease caused by an infection by human immunodeficiency virus (HIV-1, HIV-2), a retrovirus that causes immune system failure and debilitation and is often accompanied by infections such as tuberculosis. AIDS is spread through direct contact with bodily fluids.
Acronym: AIDS
(10 May 1997)
murine acquired immunodeficiency syndrome <syndrome> Acquired defect of cellular immunity that occurs in mice infected with mouse leukaemia viruses (mulv). The syndrome shows striking similarities with human aids and is characterised by lymphadenopathy, profound immunosuppression, enhanced susceptibility to opportunistic infections, and B-cell lymphomas.
(12 Dec 1998)
simian acquired immunodeficiency syndrome <syndrome> Acquired defect of cellular immunity that occurs naturally in macaques infected with srv serotypes, experimentally in monkeys inoculated with srv or mason-pfiser monkey virus (mpmv), or in monkeys infected with siv.
(12 Dec 1998)
feline acquired immunodeficiency syndrome <syndrome> Acquired defect of cellular immunity that occurs in cats infected with feline immunodeficiency virus (fiv) and in some cats infected with feline leukaemia virus (felv).
(12 Dec 1998)
acquired immunodeficiency disease Acquired immunodeficiency disease: Disease caused by infection with the human immunodeficiency virus (HIV).
(12 Dec 1998)
combined immunodeficiency syndrome <syndrome> A serious primary immunodeficiency affecting both T and B-cells.
(05 Mar 2000)
immunodeficiency syndrome <syndrome> An immunological deficiency or disorder, of which the chief symptom is an increased susceptibility to infection, the pattern of susceptibility being dependent upon the kind of deficiency.
See: immunodeficiency.
(05 Mar 2000)
bovine immunodeficiency virus A lentivirus causing lymphocytosis in cattle.
(05 Mar 2000)
malignancy and immunodeficiency <radiology> High risk of malignancy (especially lymphoma/leukaemia, GI tumours): X-linked agammaglobulinaemia (Bruton's), common variable immunodeficiency, severe combined immunodeficiency (SCID kids), ataxia-telangectasia, Wiscott-Aldrich syndrome, selective IgA deficiency
(12 Dec 1998)
cellular immunodeficiency with abnormal immunoglobulin synthesis An ill-defined group of sporadic disorders of unknown cause, occurring in both males and females and associated with recurrent bacterial, fungal, protozoal, and viral infections; there is thymic hypoplasia with depressed cellular (T-lymphocyte) immunity combined with defective humoral (B-lymphocyte) immunity, although immunoglobulin levels may be normal.
Synonym: Nezelof syndrome, Nezelof type of thymic alymphoplasia.
(05 Mar 2000)
phagocytic dysfunction disorders immunodeficiency Suppression in number or function of phagocytic cells such as in chronic granulomatous disease.
Synonym: phagocytic dysfunction disorders immunodeficiency.
Origin: L. Phagedaena, Gr Phago, To eat.
(05 Mar 2000)
phagocytic dysfunction immunodeficiency Suppression in number or function of phagocytic cells such as in chronic granulomatous disease.
Synonym: phagocytic dysfunction disorders immunodeficiency.
Origin: L. Phagedaena, Gr Phago, To eat.
(05 Mar 2000)
combined immunodeficiency <immunology> Congenital immunodeficiency with thymic agenesis, lymphocyte depletion and hypogammaglobulinaemia: both cellular and humoral immune systems are affected and life expectancy is low unless marrow transplantation is successful.
(18 Nov 1997)
common variable immunodeficiency Heterogeneous group of immunodeficiency syndromes characterised by hypogammaglobulinaemia of most isotypes, variable B-cell defects, and the presence of recurrent bacterial infections.
(12 Dec 1998)
congenital severe combined immunodeficiency Disease, one form of which is caused by the lack of a transcription factor required for expression of HLA class II genes.
(18 Nov 1997)
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