| 영문 | cytokine | 한글 | 시토카인 |
|---|---|---|---|
| 설명 | 조직의 국소에서 생산되어서 국소의 세포간의 신호전달을 매개하는 단백질 인자의 총칭이다. 표적세포의 수용체에 결합해서 세포내 활성화 메커니즘을 발현시키는 것으로 면역반응의 제어, 항암작용, 항바이러스작용, 세포의 증식-분화의 조절 등의 작용을 나타낸다. 일반적으로 10－12~10－10 몰의 극히 미량에서 기능하며 신속히 분해소실된다. 림프구가 분비하는 림포카인, 큰포식세포 유래의 모노카인, T세포가 분비하는 인터루킨 등의 여러 종류가 알려지고 있으나 각각의 유전자의 해명으로 동일한 것이 판명되고 있다. |
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| 영문 | serum proteins | 한글 | 혈청단백 |
|---|---|---|---|
| 설명 | 혈청에 있는 단백질들을 총칭하는 말로, 면역글로불린(면역현상에 관여하는 항체를 형성함), 알부민, 보체 및 응고인자와 여러 효소들이 이에 속한다. |
||
| CRF | case report form; chronic renal failure; chronic respiratory failure; coagulase-reacting factor; con... |
|---|---|
| CSIF | cytokine synthesis inhibitory factor |
| PBPs | Penicillin-Binding Proteins |
| PVM | pneumonia virus of mice; proteins, vitamins, and minerals |
| RPSP | reference preparation for serum proteins |
| Socs | Suppressor of Cytokine Signaling |
|---|---|
| RGS proteins | Regulators of G protein signaling |
| SOCS-1 | suppressor of cytokine signalling-1 |
| SOCS3 | suppressor of cytokine signalling 3 |
| G proteins | GIP-binding proteins |
| receptors, cytokine | Cell surface proteins that bind cytokines and trigger intracellular changes influencing the behaviour of cells. (12 Dec 1998) |
|---|---|
| cytokine | <biochemistry> Small proteins or biological factors (in the range of 5-20 kD) that are released by cells and have specific effects on cell-cell interaction, communication and behaviour of other cells. Not really different from hormones, but the term tends to be used as a convenient generic shorthand for interleukins, lymphokines and several related signalling molecules such as TNF and interferons. Generally growth factors would not be classified as cytokines, though TGF is an exception. Rather an imprecise term. Chemokines are a subset of cytokines. (29 Sep 1997) |
| second signaling system | <psychology> Pavlovian term for speech in which words are considered to be the second signals capable of producing conditioned responses. (05 Mar 2000) |
| hydrophilic signaling molecule | <molecular biology> A type of molecule which, because it is easily dissolved in water (it is hydrophilic), can easily move through cell membranes and thus can be secreted from one cell and move into a target cell where it triggers a particular event. Many hormones and growth factors are hydrophilic signaling molecules. (09 Oct 1997) |
| amber suppressor | <molecular biology> A tRNA molecule which suppresses amber mutations because it has mutated to recognise the amber codon UAG (which normally signals that the translation of mRNA into an amino acid chain should stop) as a signal for inserting whatever amino acid it carries into the chain. As a result, it can prevent the amino acid chain from ending before it is completed. (09 Oct 1997) |
| genes, suppressor | Genes that inhibit expression of a previous mutation. They allow the wild-type phenotype to be wholly or partially restored. (12 Dec 1998) |
| genes, suppressor, tumour | Genes that inhibit expression of the tumourigenic phenotype. They are normally involved in holding cellular growth in check. When tumour suppressor genes are inactivated or lost, a barrier to normal proliferation is removed and deregulated growth is possible. (12 Dec 1998) |
| suppressor | A compound that suppresses the effects of mutation or suppresses what would be a normal course of events. (05 Mar 2000) |
| suppressor cell | <immunology> Lymphocyte class of cells suppressing T or B antigen dependent responses. (18 Nov 1997) |
| suppressor cells | Cells of the immune system that inhibit or help to terminate an immune response, e.g., suppressor macrophages and suppressor T-cells. Synonym: cytotoxic cell. (05 Mar 2000) |
| suppressor factor | <immunology> Factors released by T suppressor cells. See: suppressor mutation, ochre suppressor, opal suppressor. (19 Jan 1998) |
| suppressor factors, immunologic | Proteins, protein complexes, or glycoproteins secreted by suppressor T-cells that inhibit either subsequent T-cells, B-cells, or other immunologic phenomena. Some of these factors have both histocompatibility (I-j) and antigen-specific domains which may be linked by disulfide bridges. They can be elicited by haptens or other antigens and may be mass-produced by hybridomas or monoclones in the laboratory. (12 Dec 1998) |
| suppressor mutation | <molecular biology> Mutation that alleviates the effect of a primary mutation at a different locus. May be through almost any mechanism that can give a primary mutation, but perhaps the most interesting class are the amber and ochre supressors, where the anticodon of the tRNA is altered so that it mis reads the termination codon and inserts an amino acid, preventing premature termination of the peptide chain. (18 Nov 1997) |
| suppressor-sensitive mutant | A conditionally lethal, host range, bacteriophage mutant that produces nonsense codons and can replicate only in a host bacterium able to translate the nonsense codon; the mutation's effects are lethal (i.e., prevent replication of the virus) in a bacterium without such a suppressor mechanism. (05 Mar 2000) |
| suppressor T-cell | <immunology> See T-cells. (18 Nov 1997) |
Synonyms : SOCS Proteins, Suppressors of Cytokine Signaling Proteins
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|