| congenital severe combined immunodeficiency | Disease, one form of which is caused by the lack of a transcription factor required for expression of HLA class II genes. (18 Nov 1997) |
|---|---|
| severe combined immunodeficiency | Group of rare congenital disorders characterised by impairment of both humoral and cell-mediated immunity, leukopenia, and low or absent antibody levels. It is inherited as an x-linked or autosomal recessive defect. About half of the patients with autosomal recessive scid are deficient in the enzyme adenosine deaminase. (12 Dec 1998) |
| severe combined immunodeficient mice | Mice that lack both T and B lymphocytes and are used for transplantation and study of human lymphoid tissues resulting in a SCID-human mouse chimera. See: severe combined immunodeficiency. (05 Mar 2000) |
| severe postanoxic encephalopathy | Coma that develops a few days to 3 weeks after an acute hypoxic insult; the latter was usually severe enough to cause an initial bout of coma, which cleared, and was followed by a transient interval of apparent normality. Synonym: severe postanoxic encephalopathy. (05 Mar 2000) |
| Arneth formula | The normal, approximate ratio of polymorphonuclear neutrophils, based on the number of lobes in the nuclei, as follows: 1 lobe, 5%; 2 lobes, 35%; 3 lobes, 41%; 4 lobes, 17%; 5 lobes, 2%. (05 Mar 2000) |
| Bazett's formula | A formula for correcting the observed Q-T interval in the electrocardiogram for cardiac rate: corrected Q-T = Q-T sec/✓R -R sec. (05 Mar 2000) |
| Bernhardt's formula | <nutrition> A formula used to calculate the ideal weight, in kilograms, for an adult; it is the height in centimeters times the chest circumference in centimeters divided by 240. (14 Aug 2000) |
| Black's formula | A translation of Pignet's formula into British measurements: F = (W + C) -H; F is the empirical factor, W is the weight in pounds, C the chest girth in inches at full inspiration, and H the height in inches; a man is classed as very strong when F is over 120, strong between 110 and 120, good 100 to 110, fair 90 to 100, weak 80 to 90, very weak under 80. (05 Mar 2000) |
| Broca's formula | A fully developed man (30 years old) should weigh as many kilograms as he is centimeters in height over and above 1 meter. (05 Mar 2000) |
| Van Slyke's formula | The value obtained when the square root of the urine flow (when below 2 ml/min) is multiplied by the urine urea concentration and divided by the whole blood urea concentration; represents an old empirical adjustment for the effect of low urine flow on urea excretion; sometimes corrected for body size by dividing by some function of body weight or surface area. Later, plasma concentration was substituted for blood concentration in the calculation. The normal value is about 54 ml/min per 1.73 m2 in an adult person. Synonym: Van Slyke's formula. (05 Mar 2000) |
| Mall's formula | A formula for determining the age (in days) of a human embryo; calculated as the square root of its length (measured from vertex to breech) in millimeters multiplied by 100. (05 Mar 2000) |
| Ranke's formula | A = grams of albumin per liter of a serous fluid: then, A = (sp. Gr. -1000) × 0.52 -5.406. (05 Mar 2000) |
| rational formula | In chemistry, a formula that indicates the constitution as well as the composition of a substance. (05 Mar 2000) |
| genomic formula | <molecular biology> The method used to identify the number of sets of chromosomes within a cell or organism (i.e. Its ploidy). Each set is designated n so one set is n is haploid, two sets is 2n is diploid, three sets is 3n is triploid, four sets is 4n is tetraploid, etc. Also, 2n+1 is known as trisomy (i.e. Two full sets plus a third copy of one of the chromosomes). (09 Oct 1997) |
| vertebral formula | A formula indicating the number of vertebrae in each segment of the spinal column; for man it is C. 7, T. 12, L. 5, S. 5, Co. 4 = 33, the letters standing for cervical, thoracic, lumbar, sacral, and coccygeal. (05 Mar 2000) |