Steroid 17-alpha-Hydroxylase : KMLE 의학 검색 엔진 - 의학사전, 의학용어, 의학약어, 의학논문, 약품/의약품 검색

MeSH(Medical Subject Headings) 맞춤 검색 (http://www.nlm.nih.gov) 결과 : 1 페이지: 1

Steroid 17-alpha-Hydroxylase - 새창 A microsomal cytochrome P450 enzyme that catalyzes the 17-alpha-hydroxylation of progesterone or pregnenolone and subsequent cleavage of the residual two carbons at C17 in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP17 gene, generates precursors for glucocorticoid, androgen, and estrogen synthesis. Defects in CYP17 gene cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL) and abnormal sexual differentiation.
Synonyms : 17 alpha-Hydroxylase Cytochrome P-450, 17 alpha-Hydroxyprogesterone Aldolase, 17, 20-Desmolase, Cytochrome P-450(17-alpha), Cytochrome P450(17 alpha), Hydroxyprogesterone Aldolase, Steroid 17 alpha-Hydroxylase, Steroid-17-Hydroxylase, 17 alpha Hydroxylase