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"Soulier"에 대한 영영 의학사전 세부 검색 결과입니다
CancerWEB 영영 의학사전 맞춤 검색 결과 : 1 페이지: 1
Soulier, Jean Pierre <person> French haematologist, *1915.
See: Bernard-Soulier disease, Bernard-Soulier syndrome.
(05 Mar 2000)
CancerWEB 영영 의학사전 유사 검색 결과 : 2 페이지: 1
Bernard-Soulier disease An autosomal recessive disorder of absent or decreased platelet membrane glycoproteins Ib, IX, and V (the receptor for factor VIII R. This deficiency can lead to a failure to bind von Willebrand factor, causing moderate bleeding.
(05 Mar 2000)
Bernard Soulier syndrome <haematology, syndrome> A congenital disorder where the platelets lack receptors which allow them to adhere to the walls of blood vessels. The genetic deficiency in platelet membrane glycoprotein Ib allows platelets to aggregate normally (c.f. Glanzmann's thrombasthenia) but they do not stick to collagen of sub endothelial basement membrane. The net result is a platelet function disorder that causes a prolonged bleeding time.
Symptoms include nosebleeds, easy bruising, heavy menstrual periods, bleeding gums and increased post-operative bleeding. Avoidance of aspirin, anti-inflammatories or any other agents which can cause bleeding is critical.
(06 Oct 1997)
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