| small cell lung cancer | A type of lung cancer in which the cells are small and round. Also called oat cell lung cancer. (12 Dec 1998) |
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| carcinoma, non-small-cell lung | A heterogeneous aggregate of at least three distinct histological types of lung cancer, including squamous cell carcinoma, adenocarcinoma, and large cell carcinoma. They are dealt with collectively because of the shared properties of poor response to conventional chemotherapy and the potential for cure with surgical resection in a fraction of patients. (12 Dec 1998) |
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| nonsmall cell lung cancer | A general classification for squamous cell carcinoma, adenocarcinoma, and large cell carcinoma. (12 Dec 1998) |
| cancer, lung | Cancer of the major organ of respiration the lung. Lung cancer kills more men and women than any other form of cancer. Since the majority of lung cancer is diagnosed at a relatively late stage, only 10% of all lung cancer patients are ultimately cured. Eight out of 10 lung cancers are due to tobacco smoke. Lung cancers are classified as either small cell or non-small cell cancers. Persistent cough and bloody sputum can be symptoms of lung cancer. Lung cancer can be diagnosed based on examination of sputum, or tissue examination with biopsy using bronchoscopy, needle through the chest wall, or surgical excision. (12 Dec 1998) |
| metastatic cancer to the lung | The spread of cancerous tumours from a distant organ to the lung. Due to the lungs tremendous blood and lymphatic supply it is a frequent site for metastatic cancer. Cancers which commonly metastasize to the lung include osteosarcoma, breast cancer, neuroblastoma, Wilm's tumour and non-Hodgkin's lymphomas. (27 Sep 1997) |
| metastatic lung cancer | The spread of cancerous tumours from a distant organ to the lung. Due to the lungs tremendous blood and lymphatic supply it is a frequent site for metastatic cancer. Cancers which commonly metastasize to the lung include osteosarcoma, breast cancer, neuroblastoma, Wilm's tumour and non-Hodgkin's lymphomas. (27 Sep 1997) |
| secondary lung cancer | The spread of cancerous tumours from a distant organ to the lung. Due to the lungs tremendous blood and lymphatic supply it is a frequent site for metastatic cancer. Cancers which commonly metastasize to the lung include osteosarcoma, breast cancer, neuroblastoma, Wilm's tumour and non-Hodgkin's lymphomas. (27 Sep 1997) |
| lung cancer | A cancerous growth in lung tissue. Lung cancer may be metastatic from another source (colon) or may be primary (tumour is of lung cell origin). Classification is based on the type of cell the lung cancer originates from (adenocarcinoma, alveolar cell carcinoma, squamous cell carcinoma, large cell and small cell carcinomas). (27 Sep 1997) |
| carcinoma, small cell | An anaplastic, highly malignant, and usually bronchogenic carcinoma composed of small ovoid cells with scanty neoplasm. It is characterised by a dominant, deeply basophilic nucleus, and absent or indistinct nucleoli. There are admixtures of small cell lung carcinoma with other types of lung cancer. Small cell carcinomas are distinguished by their distinctive biological features, response to chemotherapy and radiotherapy, and by their nearly universal tendency to develop overt or subclinical metastases, which frequently eliminates surgery in most patients. (12 Dec 1998) |
| sarcoma, small cell | A sarcoma characterised by the presence of small cells, cells measuring 9-14 micrometers with a faint or indistinct rim of cytoplasm and an oval-to-elongated nucleus with relatively dense chromatin. (12 Dec 1998) |
| small cell carcinoma | <oncology, tumour> Common malignant neoplasm of bronchus. Cells of the tumour have endocrine like characteristics and may secrete one or more of a wide range of hormones, especially regulatory peptides like bombesin. (18 Nov 1997) |
| small cleaved cell | A lymphoid cell of follicular centre cell origin that has an irregularly shaped nucleus with clumped chromatin, absent nucleoli, and one or more clefts in the nuclear membrane. (05 Mar 2000) |
| diffuse small cleaved cell lymphoma | <tumour> A diffuse poorly differentiated lymphocytic lymphoma; follicular centre cell lymphoma that lacks a follicular pattern; malignancy is of intermediate grade. (05 Mar 2000) |
| follicular predominantly small cleaved cell lymphoma | <tumour> A B-cell lymphoma with nodular or diffuse lymph node or bone marrow involvement by large lymphoid cells. Synonym: follicular predominantly small cleaved cell lymphoma, nodular histiocytic lymphoma. (05 Mar 2000) |
| lymphoma, small-cell | A B-cell lymphoma presumably representing a tumour of interfollicular B-lymphocytes that may be functional. Those that are secrete identical immunoglobulin molecules. (12 Dec 1998) |
| lymphoma, small cleaved-cell, diffuse | An intermediate-grade malignant lymphoma in which the neoplastic cells (B-lymphocytes) exhibit variability in size, configuration, and degree of differentiation. The cells have distinctive nuclei, irregular in shape, with marked indentations and angularity. (12 Dec 1998) |