| Silber, Robert | <person> U.S. Biochemist, *1915. See: Porter-Silber chromogens, Porter-Silber reaction, Porter-Silber chromogens test. (05 Mar 2000) |
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| Porter-Silber chromogens test | A test, dependent on the Porter-Silber reaction, that is used as a measure of adrenocortical function and is performed on urine. Low values are seen in Addison's disease and hypopituitarism; high values are seen in Cushing's syndrome and extreme stress. Synonym: 17-OH-corticoids test, Porter-Silber chromogens test. (05 Mar 2000) |
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| Porter-Silber reaction | The basis of the 17-hydroxycorticosteroid test; C-21 adrenocorticosteroids, which contain a dihydroxyacetone group at carbons 19, 20, and 21, react with phenylhydrazine. (05 Mar 2000) |