| progressive familial scleroderma | A syndrome characterised by calcinosis cutis, Raynaud's phenomenon, sclerodactyly, and telangiectasia; usually due to scleroderma; autosomal dominant form of progressive systemic sclerosis. (05 Mar 2000) |
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| scleroderma | <dermatology> Hardening of skin. (04 Mar 1998) |
| scleroderma, circumscribed | A chronic, localised hardening and thickening of the skin. Lesions may be categorised as morphea (guttate, profunda, pansclerotic) or linear (with or without melorheostosis or hemiatrophy). It is twice as common in women as in men. The condition is characterised by skin ischemia, lymphocytic infiltrates, swollen collagen bundles, and thickening of the dermis with reduction of subcutaneous fat. (12 Dec 1998) |
| scleroderma, systemic | A chronic, progressive dermatosis characterised by boardlike hardening and immobility of the affected skin, with visceral involvement, especially of lungs, oesophagus, kidneys and heart. It may be accompanied by calcinosis, raynaud's phenomenon, and telangiectasis (crest syndrome). It includes acrosclerosis and sclerodactyly. (12 Dec 1998) |
| self-limited | Denoting a disease that tends to cease after a definite period; e.g., pneumonia. (05 Mar 2000) |
| self-limited disease | A disease process that resolves spontaneously with or without specific treatment. (05 Mar 2000) |
| sex-limited | Occurring in one sex only. See: sex-limited inheritance. (05 Mar 2000) |
| sex-limited inheritance | Inheritance of a trait that can be expressed in one sex only, e.g., testicular feminization. (05 Mar 2000) |
| oesophagus: scleroderma | <radiology> Females (80%), 35-55 years of age, decreased LES pressure, decreased peristalsis, smooth muscle atrophy with or without loose fibrosis, dermatomyositis may include involvement of upper 1/3 (striated), dysphagia to solids more than liquids (steakhouse syndrome), wide-open LES or HH, with or without basilar pulmonary fibrosis, other GI sites associated with CREST syndrome (12 Dec 1998) |
| limited habitat | A habitat type that is rare or has been significantly reduced from its historical distribution, either locally or statewide, and is of special importance meeting the general life requirements of many wildlife species. (09 Oct 1997) |
| limited range audiometer | A pure-tone audiometer designed to test restricted ranges of frequency and sound pressure. (05 Mar 2000) |
| localised scleroderma | A skin lesion that is characterised by the presence of localised, indurated, slightly depressed areas of thickened dermal tissue that may be white or yellow in colour and surrounded by a pink or purplish halo. See: in cutaneus scleroderma. (27 Sep 1997) |