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Schilling type of monocytic leukaemia See: monocytic leukaemia.
(05 Mar 2000)
leukemia <haematology> An acute or chronic disease of unknown cause in man and other warm blooded animals that involves the blood forming organs, is characterised by an abnormal increase in the number of leucocytes in the tissues of the body with or without a corresponding increase of those in the circulating blood and is classified according of the type leucocyte most prominently involved.
(18 Nov 1997)
Naegeli type of monocytic leukaemia A variant of granulocytic leukaemia with monocytosis in the peripheral blood.
Synonym: Naegeli type of monocytic leukaemia.
(05 Mar 2000)
Schilling's band cell <pathology> Immature neutrophils released from the bone marrow reserve in response to acute demand.
(18 Nov 1997)
Schilling's blood count A method of counting blood in which the polymorphonuclear neutrophils are separated into four groups according to the number and arrangement of the nuclear masses in these cells.
Synonym: Schilling's index.
(05 Mar 2000)
Schilling's index A method of counting blood in which the polymorphonuclear neutrophils are separated into four groups according to the number and arrangement of the nuclear masses in these cells.
Synonym: Schilling's index.
(05 Mar 2000)
schilling test <investigation> This test measures the amount of vitamin B12 in the urine after ingesting a dose of B12. This test evaluates vitamin B12 absorption. The cells in the stomach produce a substance known as intrinsic factor. This substance combines with B12 to allow absorption in the distal ileum. The patient is given a small dose of radioactive B12 which can then be detected in the patients urine. Pernicious anaemia is the clinical result of B12 deficiency. Conditions that can result in an abnormal Schilling test include: deficiency of intrinsic factor, malabsorption or the development of an antibody to intrinsic factor. The Schilling test can be performed with or without administration of intrinsic factor to determine what the underlying cause for pernicious anaemia. Laxative use, renal insufficiency and hypothyroidism can all interfere with the results of this test.
(27 Sep 1997)
Schilling, Victor <person> German haematologist, 1883-1960.
See: Schilling's blood count, Schilling's band cell, Schilling's index, Schilling test, Schilling type of monocytic leukaemia.
(05 Mar 2000)
acute monocytic leukaemia <haematology> The most common translocation in this disorder of poorly differentiated monocytic cells involves chromosome region 11q in a large percentage of cases.
The translocation involves a cellular oncogene, c-ets which is mapped to the 11q23-24 region. The most common translocations reported are t(6;11), t(9;11), t(11;17) and t(11;19), of which t(9;11) (p21-22;q23) is by far the most frequently detected and implicated in acute myeloid leukaemia. The cells express CD14 surface antigen, which is diagnostic of monocytic cells.
Acronym: AML
Classification: FAB M5
(07 Apr 1998)
monocytic angina An obsolete term for infectious mononucleosis.
(05 Mar 2000)
monocytic leukaemia Cancer of the blood due to proliferation of cells of the monocyte series.
Origin: Gr. Haima = blood
(13 Nov 1997)
monocytic leukemoid reaction Leukocytosis of varying degree, e.g., 30,000 to 40,000 per cu mm, with adult monocytes and immature forms amounting to 30% (or more) of the total number of white blood cells in the circulating blood; may be observed in association with tuberculosis, especially the first infection, miliary type.
(05 Mar 2000)
monocytic leukocytosis An abnormal increase in the number of monocytes in the circulating blood.
Synonym: monocytic leukocytosis.
(05 Mar 2000)
monocytic leukopenia Diminution in the number of monocytes in the circulating blood.
Synonym: monocytic leukopenia, monopenia.
Origin: mono-+ G. Kytos, cell, + penia, poverty
(05 Mar 2000)
equine monocytic ehrlichiosis <veterinary> A febrile disease of horses in North America caused by Ehrlichia risticii and characterised by anorexia, leukopenia, and occasional diarrhoea.
Synonym: Potomac horse fever.
(05 Mar 2000)
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