| saquinavir |
a weak protease inhibitor (trade name Invirase) used in treating HIV
출처: wordnet.princeton.edu/perl/webwn
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| saquinavir mesylate |
A drug that belongs to the family of drugs called protease inhibitors. It interferes with the ability of a virus to make copies of itself.
출처: www.stjude.org/glossary
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| saquinavir |
Saquinavir hard-gel capsule 27 (Invirase) was the first PI approved by the FDA, in December 1995. A carboxamide derivative specifically designed to inhibit HIV proteinase and prevent post-translational formation of viral proteins, saquinavir is a potent inhibitor of HIV-1 and HIV-2 proteinases without prior metabolic activation. At 12 nM concentration, saquinavir has a 50% inhibition of normal HIV, and at 11 nM it has a 50% inhibition of ZDV-resistant HIV.
출처: www.ascp.com/public/pubs/tcp/1998/nov/hivaids.shtm...
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