STAT : KMLE 의학 검색 엔진 - 의학사전, 의학용어, 의학약어, 의학논문, 약품/의약품 검색

MeSH(Medical Subject Headings) 맞춤 검색 (http://www.nlm.nih.gov) 결과 : 5 페이지: 1

STAT Transcription Factors - 새창 A family of transcription factors containing SH2 DOMAINS that are involved in CYTOKINE-mediated SIGNAL TRANSDUCTION. STAT transcription factors are recruited to the cytoplasmic region of CELL SURFACE RECEPTORS and are activated via PHOSPHORYLATION. Once activated they dimerize and translocate into the CELL NUCLEUS where they influence GENE expression. They play a role in regulating CELL GROWTH PROCESSES and CELL DIFFERENTIATION. STAT transcription factors are inhibited by SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS and PROTEIN INHIBITORS OF ACTIVATED STAT.
Synonyms : STAT (Signal Transducers and Activators of Transcription) Proteins, Transcription Factors, STAT
STAT1 Transcription Factor - 새창 A signal transducer and activator of transcription that mediates cellular responses to INTERFERONS. Stat1 interacts with P53 TUMOR SUPPRESSOR PROTEIN and regulates expression of GENES involved in growth control and APOPTOSIS.
Synonyms : Gamma-Activated Factor, 91 kDa, STAT-91 Protein, STAT-91 Transcription Factor, STAT1 Protein, STAT91 Transcription Factor, Signal Transducer and Activator of Transcription 1, Transcription Factor STAT91, Gamma Activated Factor, 91 kDa, STAT 91 Protein
STAT2 Transcription Factor - 새창 A signal transducer and activator of transcription that mediates cellular responses to TYPE I INTERFERONS. Stat2 protein is associated constitutively with INTERFERON REGULATORY FACTOR-9. After PHOSPHORYLATION Stat2 forms the IFN-STIMULATED GENE FACTOR 3 COMPLEX to regulate expression of target GENES.
Synonyms : STAT2 Protein, Signal Transducer and Activator of Transcription 2, Transcription Factor STAT2, Factor STAT2, Transcription, Transcription Factor, STAT2
STAT3 Transcription Factor - 새창 A signal transducer and activator of transcription that mediates cellular responses to INTERLEUKIN-6 family members. STAT3 is constitutively activated in a variety of TUMORS and is a major downstream transducer for the CYTOKINE RECEPTOR GP130.
Synonyms : APRF Transcription Factor, Acute-Phase Response Factor, IL6-Response Factor, LIF-Response Factor, STAT3 Protein, STAT3a Transcription Factor, STAT3b Transcription Factor, Signal Transducer and Activator of Transcription 3, Stat3alpha Transcription Factor
STAT4 Transcription Factor - 새창 A signal transducer and activator of transcription that mediates cellular responses to INTERLEUKIN-12 in T-LYMPHOCYTES. Stat4 is an important signaling molecule for differentiation in TH1 CELLS.
Synonyms : STAT4 Protein, STAT4A Transcription Factor, STAT4alpha Protein, STAT4b Transcription Factor, STAT4beta Protein, Signal Transducer and Activator of Transcription 4, Transcription Factor STAT4, Transcription Factor, STAT4, Transcription Factor, STAT4A